Aftab Sadqa, Khan Abdul Bari, Raza Ghulam
Department of Anaesthesiology, Dow University of Health Sciences, Karachi.
J Coll Physicians Surg Pak. 2008 Mar;18(3):137-41.
To determine the risk factors for postoperative nausea and vomiting.
Quasi-experimental study with prospective data collection.
The study was conducted at Dow Medical College University and Civil Hospital, Karachi from January to December 2004.
Data on patients' characteristic, anesthesia, surgery and postoperative nausea and vomiting was collected in operating theatre, postanesthesia care unit and wards.
During postoperative 24 hours period, 60 out of a total of 200 patients experienced nausea and vomiting. The factors associated with an increased risk of Postoperative Nausea and Vomiting (PONV) were gender (female odds ratio 3), patients with previous history of nausea and vomiting or motion sickness (odds ratio 4), laparoscopic cholecystectomy (odds ratio 3.5) and eye surgery (odds ratio 3.9), all of these were statistically significant (p<0.05). No statistically significant difference was found between the other parameters.
The incidence of PONV was found significantly higher in female gender, patients with previous history of nausea and vomiting or motion sickness, patient undergoing laparoscopic cholecystectomy and eye surgery.
确定术后恶心呕吐的危险因素。
采用前瞻性数据收集的准实验研究。
该研究于2004年1月至12月在卡拉奇的道医学大学和市民医院进行。
在手术室、麻醉后护理单元和病房收集患者特征、麻醉、手术及术后恶心呕吐的数据。
在术后24小时内，200名患者中有60名出现恶心呕吐。与术后恶心呕吐（PONV）风险增加相关的因素有性别（女性优势比为3）、有恶心呕吐或晕动病史的患者（优势比为4）、腹腔镜胆囊切除术（优势比为3.5）和眼科手术（优势比为3.9），所有这些均具有统计学意义（p<0.05）。其他参数之间未发现统计学显著差异。
发现女性、有恶心呕吐或晕动病史的患者、接受腹腔镜胆囊切除术和眼科手术的患者中PONV的发生率显著更高。
