Yildirim Gazi, Ficicioglu Cem, Akcin Oya, Attar Rukset, Tecellioglu Nihan, Yencilek Faruk
Department of Obstetrics and Gynecology, Yeditepe University Hospital, Devlet Yolu, Ankara Cad. No: 102-104, Kozyatagi, Istanbul, Turkey.
Arch Gynecol Obstet. 2009 Feb;279(2):213-5. doi: 10.1007/s00404-008-0671-y. Epub 2008 May 7.
Primary ciliary dyskinesia (PCD), previously known as immotile cilia syndrome, can cause respiratory and reproductive problems. Because of the impaired motion of microtubules the patients suffer upper respiratory tract problems. Infertility is an other issue of these patients. Several attempt have been proposed to bring back sperm motion and to improve intracytoplasmic sperm injection (ICSI) results. With our case we have described the management of a male infertility that causes from immotile cilia. The role of ICSI with incubated and activated ejaculatory sperm by pentoxifylline in the patient of PCD or as commonly named immotile cilia syndrome.
原发性纤毛运动障碍(PCD),以前称为不动纤毛综合征,可导致呼吸和生殖问题。由于微管运动受损,患者会出现上呼吸道问题。不孕是这些患者的另一个问题。已经提出了几种尝试来恢复精子活力并改善胞浆内单精子注射(ICSI)的结果。通过我们的病例,我们描述了由不动纤毛引起的男性不育症的治疗方法。在原发性纤毛运动障碍患者或通常所说的不动纤毛综合征患者中,使用己酮可可碱孵育和激活射出精子进行胞浆内单精子注射的作用。