Lauridsen Mette Cathrine, Overgaard Marie, Overgaard Jens, Hessov I B, Cristiansen Peer
Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark.
Acta Oncol. 2008;47(4):569-75. doi: 10.1080/02841860801986627.
Axillary dissection in combination with radiation therapy is thought to be the main reason why patients surgically treated for breast cancer may develop decreased shoulder mobility on the operated side. The surgery performed on the breast has not been ascribed any considerable importance. In order to evaluate the influence of the surgical technique and the adjuvant oncological therapy on the development of shoulder morbidity, we assessed the physical disability in 132 breast cancer patients with a median follow-up time of 3 years after surgery.
Eighty nine (67%) patients had been subjected to modified radical mastectomy and 43 (33%) to breast conserving therapy (BCT). All patients had axillary dissection of level I and II. The shoulder function was assessed by the Constant Shoulder Score including both subjective parameters on pain and ability to perform the normal tasks of daily living, and objective parameters assessing active range of motion and muscle strength.
Shoulder disability seems to be a frequent late complication to the treatment of early breast cancer (35%). When equal axillary dissection and radiation therapy had been applied, BCT patients were found to suffer less frequent from this complication than patients treated with mastectomy.
腋窝清扫联合放射治疗被认为是接受乳腺癌手术治疗的患者患侧肩部活动度降低的主要原因。而乳房手术本身并未被认为具有太大影响。为了评估手术技术和辅助肿瘤治疗对肩部并发症发生的影响,我们对132例乳腺癌患者进行了评估,这些患者术后中位随访时间为3年。
89例(67%)患者接受了改良根治性乳房切除术,43例(33%)接受了保乳治疗(BCT)。所有患者均进行了I级和II级腋窝清扫。通过Constant肩部评分评估肩部功能,该评分包括疼痛的主观参数和进行日常生活正常任务的能力,以及评估主动活动范围和肌肉力量的客观参数。
肩部功能障碍似乎是早期乳腺癌治疗常见的晚期并发症(35%)。在腋窝清扫和放射治疗相同的情况下,发现接受保乳治疗的患者出现这种并发症的频率低于接受乳房切除术的患者。