Bergeron Chris M, Moe Kris S
Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Harborview Medical Center, Seattle, Washington 98104-2420, USA.
Facial Plast Surg. 2008 May;24(2):220-30. doi: 10.1055/s-2008-1075838.
Patients with upper lid paralysis suffer from a loss of the blink reflex/response in the affected eye, leaving the eye vulnerable to a host of predatory insults. Partial or total impairment of the orbicularis oculi muscle, lagophthalmos, disruption of the lacrimal apparatus, upper lid retraction, and the unopposed pull of gravity on the surrounding paralyzed tissues all contribute to increased corneal exposure and an increased risk of exposure keratitis. Management of the upper lid in these patients must therefore focus on restoration of the effects of the blink reflex/response and prevention of corneal exposure. Relevant anatomy and pathophysiology are discussed. The initial treatment is supportive, with surgery reserved for those patients that fall into two categories: those who have failed nonsurgical treatment to protect the cornea and those who have been treated effectively with conservative measures but are faced with the prospect of long-term or permanent paralysis. A variety of surgical procedures that may be classified as either static or dynamic are discussed. Standard static procedures include lid loading and tarsorrhaphy, whereas the palpebral spring implant and the temporalis muscle transfer are classified as dynamic. The goal of the corrective procedures is to allow complete eye closure, thereby providing corneal protection, with minimal (1 mm or less) ptosis in the open position.
上睑麻痹患者患侧眼睛的瞬目反射/反应丧失,使眼睛易受多种侵害。眼轮匝肌部分或完全受损、兔眼、泪器破坏、上睑退缩以及重力对周围麻痹组织的无对抗牵拉,均会导致角膜暴露增加和暴露性角膜炎风险升高。因此,这些患者上睑的治疗必须侧重于恢复瞬目反射/反应的作用并预防角膜暴露。本文讨论了相关的解剖学和病理生理学。初始治疗为支持性治疗,手术仅适用于两类患者:非手术治疗未能有效保护角膜的患者,以及经保守治疗有效但面临长期或永久性麻痹的患者。本文还讨论了多种可分为静态或动态的外科手术。标准的静态手术包括眼睑负重术和睑裂缝合术,而睑弹簧植入术和颞肌转移术则属于动态手术。矫正手术的目标是实现完全闭眼,从而保护角膜,同时睁眼时上睑下垂最小(1毫米或更小)。