磷脂衍生介质与肾小球肾炎。
Phospholipid derived mediators and glomerulonephritis.
机构信息
21 Common Road North Leigh Oxon OX8 6RD UK.
出版信息
Mediators Inflamm. 1993;2(2):99-102. doi: 10.1155/S0962935193000134.
Abstract
The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists. Combined thromboxane synthetase and thromboxane receptor antagonism would seem to be the more efficacious approach for the various disease entities.
摘要
本文综述了各种类二十烷酸、PAF、HETES 和脂氧素在肾小球肾炎病理生理学中的作用。可以考虑进行 PAF、白三烯和血栓素拮抗剂的临床试验。对于各种疾病实体，联合使用血栓素合酶和血栓素受体拮抗剂似乎是更有效的方法。
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