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意大利肿瘤病房中心癌症疼痛的患病率及治疗情况:一项横断面调查

Prevalence and treatment of cancer pain in Italian oncological wards centres: a cross-sectional survey.

作者信息

Mercadante Sebastiano, Roila Fausto, Berretto Oscar, Labianca Roberto, Casilini Stefania

机构信息

La Maddalena Cancer Center, Palermo, Italy.

出版信息

Support Care Cancer. 2008 Nov;16(11):1203-11. doi: 10.1007/s00520-008-0456-7. Epub 2008 May 14.

Abstract

OBJECTIVE

The aim of this national cross-sectional survey was to draw information on pain prevalence and intensity from a large sample of patients who were admitted to oncologic centres for different reasons and to evaluate the pain treatment and possible influencing factors.

MATERIALS AND METHODS

A total of 2,655 patients completed the study. Nine hundred and one patients (34%) reported pain.

RESULTS AND DISCUSSIONS

Higher pain levels were observed in inpatients, in the presence of bone metastases, and with low levels of Eastern Cooperative Oncology Group status. The number of patients receiving strong opioids increased with the highest levels of pain. However, a significant part of patients with moderate-severe pain were not receiving appropriate medication, patients being predominantly administered non-opioid drugs. General practitioners' attitudes did not negatively influence the opioid prescription.

CONCLUSION

The results of this survey indicate a need for continuing educational and informative program in pain management for oncologists and more generally for any physician dealing with cancer patients.

摘要

目的

这项全国性横断面调查的目的是从因不同原因入住肿瘤中心的大量患者样本中获取疼痛患病率和强度信息,并评估疼痛治疗及可能的影响因素。

材料与方法

共有2655名患者完成了该研究。901名患者(34%)报告有疼痛。

结果与讨论

住院患者、存在骨转移以及东部肿瘤协作组状态较低的患者疼痛程度更高。接受强效阿片类药物治疗的患者数量随着疼痛程度的升高而增加。然而,相当一部分中重度疼痛患者未接受适当的药物治疗,主要使用的是非阿片类药物。全科医生的态度并未对阿片类药物处方产生负面影响。

结论

本次调查结果表明,需要为肿瘤学家以及更广泛地为任何治疗癌症患者的医生开展关于疼痛管理的持续教育和信息项目。

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