经骨髓活检和氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）确诊的血管内大B细胞淋巴瘤的成功治疗。
Successful treatment of intravascular large B-cell lymphoma diagnosed by bone marrow biopsy and FDG-PET scan.
作者信息
Takahashi Tohru, Minato Masashi, Tsukuda Hiroyuki, Yoshimoto Mitsuru, Tsujisaki Masayuki
机构信息
Department of hematology, Tenshi Hospital, Sapporo.
出版信息
Intern Med. 2008;47(10):975-9. doi: 10.2169/internalmedicine.47.0808. Epub 2008 May 15.
Early diagnosis of intravascular large B-cell lymphoma (IVLBCL) is difficult, but is critical for longer survival for the patients. We report a case of IVLBCL that was diagnosed with the help of FDG-PET. A 76-year-old woman was referred to us for the evaluation of her elevated serum LDH. She presented with general malaise and high fever. There were no skin lesions or neurological involvement. FDG-PET imaging showed increased uptake of FDG in the vertebra, bilateral femurs, sternum, and iliac bones. A diagnosis of IVLBCL was made by bone marrow biopsy. She was successfully treated with rituximab and modified CHOP therapy.
血管内大B细胞淋巴瘤（IVLBCL）的早期诊断较为困难，但对患者的长期生存至关重要。我们报告一例借助氟代脱氧葡萄糖正电子发射断层扫描（FDG-PET）诊断出的IVLBCL病例。一名76岁女性因血清乳酸脱氢酶（LDH）升高前来我院评估。她表现为全身不适和高热。无皮肤病变或神经受累情况。FDG-PET成像显示在椎体、双侧股骨、胸骨和髂骨处FDG摄取增加。通过骨髓活检确诊为IVLBCL。她接受利妥昔单抗和改良环磷酰胺、阿霉素、长春新碱、泼尼松（CHOP）方案治疗后取得成功。
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