Quasthoff Stefan, Möckel Claudia, Zieglgänsberger Walter, Schreibmayer Wolfgang
Department for Neurology, Medical University of Graz, Austria.
CNS Neurosci Ther. 2008 Summer;14(2):107-19. doi: 10.1111/j.1527-3458.2008.00044.x.
Tolperisone, a piperidine derivative, is assigned to the group of centrally acting muscle relaxants and has been in clinical use now for decades. The review summarizes the known pharmacokinetics, pharmacodynamics, toxicology and side effects in humans and the clinical use of tolperisone. A future perspective for further exploration of this drug is given.
托哌酮是一种哌啶衍生物,属于中枢性肌肉松弛剂,已在临床使用数十年。本综述总结了托哌酮在人体中的已知药代动力学、药效学、毒理学和副作用以及临床应用情况。并对该药物的进一步研究给出了未来展望。