Ali-Khan A S, Crundwell M, Stone C
Department of Plastic and Reconstructive Surgery, Royal Devon and Exeter Hospital, Barrack Road, Exeter EX2 5DW, UK.
J Plast Reconstr Aesthet Surg. 2009 Aug;62(8):1063-7. doi: 10.1016/j.bjps.2007.12.040. Epub 2008 May 19.
Elective pelvic lymphadenectomy is one of the enduring controversies in the management of Stage III melanoma of the groin. It can provide valuable staging information but concerns remain over the possibility of increased morbidity without the benefit of increased survival. Endoscopic lymphadenectomy of the pelvic nodes is an established procedure in the management of urological and gynaecological malignancy but is relatively novel in the management of metastatic melanoma. An endoscopic approach reduces the risks suggested to be associated with the open procedure while still providing the clinician with the benefit of improved staging information. The authors present their experience of a combined procedure in a series of eight patients undertaken between January 2005 and May 2006 at the Exeter Melanoma Unit. One patient was discovered to harbour occult pelvic nodal metastases, despite a negative pre-operative CT scan. While no complications were directly attributable to the endoscopic procedure, the only major complication was post-operative lymphoedema which occurred in one case. The authors' experience suggests a combined procedure is both feasible and safe in the Plastic Surgery Department setting for the management of Stage III melanoma of the groin. This is the first documented UK experience of this technique.
选择性盆腔淋巴结清扫术是腹股沟区Ⅲ期黑色素瘤治疗中长久以来存在争议的问题之一。它能提供有价值的分期信息,但人们仍担心其可能增加发病率而无法提高生存率。盆腔淋巴结的内镜下淋巴结清扫术在泌尿外科和妇科恶性肿瘤的治疗中是一种既定的手术方法,但在转移性黑色素瘤的治疗中相对较新。内镜手术方法降低了与开放手术相关的风险,同时仍能为临床医生提供更好的分期信息。作者介绍了他们在2005年1月至2006年5月期间于埃克塞特黑色素瘤治疗中心对8例患者进行联合手术的经验。尽管术前CT扫描结果为阴性,但仍有1例患者被发现存在隐匿性盆腔淋巴结转移。虽然没有并发症直接归因于内镜手术,但唯一的主要并发症是1例患者发生了术后淋巴水肿。作者的经验表明,在整形外科环境中,联合手术对于腹股沟区Ⅲ期黑色素瘤的治疗是可行且安全的。这是英国首次记录该技术的经验。