Confalonieri Marco
Struttura Complessa di Pneumologia, Ospedale di Cattinara, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Trieste.
Recenti Prog Med. 2008 Mar;99(3):129-33.
The development of the medical knowledge has became a multidisciplinary process that can be called life sciences. The new biotechnologies are changing the insight of pathology and medical therapy itself. So, the rule of the physician is changing together with the overwhelming centrality of the patient into the health system. Also, the evidence based medicine is no more considered a crucial task for the physician who cares the single ill person, albeit its importance is still high for health organizations. A genomic and post-genomic approach could indeed help to create an actual personalised medicine. Nevertheless, "omics" probably need the development of new bioinformatic tools capable to manage a huge amount of data by means of Grid computing. The development of the life sciences involves new formative and professional needs for the physician. The translational knowledge can be favoured by the closeness of clinical centres and basic science areas as suggested by several examples spreading all over the world. These experiences could open new exciting horizons for the medical science.
医学知识的发展已成为一个可称为生命科学的多学科过程。新生物技术正在改变病理学及医学治疗本身的见解。因此,医生的角色正在改变,患者在卫生系统中的核心地位也日益凸显。此外,循证医学对于照料个体患者的医生而言,不再被视为一项关键任务,尽管其对卫生组织仍很重要。基因组学和后基因组学方法确实有助于创建真正的个性化医疗。然而,“组学”可能需要开发新的生物信息学工具,以便通过网格计算来管理海量数据。生命科学的发展给医生带来了新的培训和专业需求。正如世界各地的一些例子所示,临床中心与基础科学领域的紧密结合有助于促进转化知识。这些经验可能为医学科学开启令人兴奋的新视野。