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接受纤溶治疗的ST段抬高型心肌梗死患者室性早搏和室性心动过速的发生率

Frequency of ventricular premature beats and ventricular tachycardia in STEMI treated with fibrinolytics.

作者信息

Horvat Davor, Grman-Fanfani Andrea, Kupres Vlasta, Grman Janko, Sporcić-Jelić Vesna

机构信息

Department of Internal Diseases, General Hospital Karlovac, Karlovac, Croatia.

出版信息

Coll Antropol. 2008 Mar;32(1):99-102.

Abstract

To determine in acute myocardial infarction with an ST elevation (STEMI) treated with fibrinolytics frequency of ventricular premature beats (VPBs) and ventricular tachycardia (VT) according to the damaged area and residual cardiac function. With anterolateral infarction with ejection fraction (EF) < 45%, incidence of VPBs < 10/h was statistically significantly reduced (p < 0.001) while incidence of VPBs > or = 10/h as well as VPBs in a pair and VT was increased (p < 0.001). With anteroseptal infarction with EF < 45%, incidence of VPBs < 10/h was statistically reduced (p = 0.06) and incidence of VPBs > 10/h, VPBs in a pair and VT was increased (p = 0.06). With inferior and inferoposterior infarction with EF < 45%, incidence of VPBs < 10/h was reduced and incidence of VPBs > or = 10/h, VPBs in a pair and VT was increased. However, such difference was not statistically significant. Along with reduced residual cardiac function, one can also expect increase in frequency of VPBs and VT in all forms of STEMI regardless the area of damage. Such frequency is significant with all forms of anterior infarction, that is to say, slightly more with anterolateral infarction in relation to anteroseptal one. However, with inferior and inferoposterior infarction this frequency of VPBs i VT is not significant.

摘要

根据梗死面积和残余心功能,确定接受纤溶治疗的ST段抬高型急性心肌梗死(STEMI)患者室性早搏(VPB)和室性心动过速(VT)的发生频率。在前壁心肌梗死伴射血分数(EF)<45%时,VPB<10次/小时的发生率有统计学显著降低(p<0.001),而VPB≥10次/小时、成对VPB及VT的发生率增加(p<0.001)。在前间隔心肌梗死伴EF<45%时,VPB<10次/小时的发生率有统计学降低(p = 0.06),VPB>10次/小时、成对VPB及VT的发生率增加(p = 0.06)。在下壁和下后壁心肌梗死伴EF<45%时,VPB<10次/小时的发生率降低,VPB≥10次/小时、成对VPB及VT的发生率增加。然而,这种差异无统计学意义。随着残余心功能降低,无论梗死面积如何,所有类型的STEMI患者VPB和VT的发生频率均可预期增加。这种频率在所有类型的前壁心肌梗死中均有显著意义,也就是说,相对于前间隔心肌梗死,前侧壁心肌梗死时的频率略高。然而,在下壁和下后壁心肌梗死中,VPB和VT的这种频率无显著意义。

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