Stäbler A, Kröner G, Seiderer M, Samtleben W
Klinikum Grosshadern, Ludwig-Maximilians-Universität München.
Rofo. 1991 May;154(5):469-74. doi: 10.1055/s-2008-1033169.
Destructive bone and joint diseases in patients on longterm haemodialysis increase in frequency and are often caused by beta 2-microglobulin-related amyloid deposits. Due to the excellent visualisation of amyloid, MRI with T1-weighted and out-of-phase gradient recalled long TR images is the diagnostic modality of choice. 5 patients, 13 to 21 years on haemodialysis, were investigated. In four patients we found involvement of the atlantoaxial region, one patient was asymptomatic, the other three had severe neurological deficiencies.
长期血液透析患者的破坏性骨与关节疾病发病率增加，且常由β2-微球蛋白相关淀粉样沉积物引起。由于淀粉样物质的良好可视化，采用T1加权和失相梯度回波长TR图像的MRI是首选的诊断方式。对5例接受血液透析13至21年的患者进行了研究。在4例患者中，我们发现寰枢椎区域受累，1例患者无症状，其他3例有严重神经功能缺损。
