在接受放化疗后完全缓解的局限期小细胞肺癌患者中，在进行预防性颅脑照射之前脑转移的发生率：单机构经验
Prevalence of brain metastases immediately before prophylactic cranial irradiation in limited disease small cell lung cancer patients with complete remission to chemoradiotherapy: a single institution experience.
作者信息
Manapov Farkhat, Klautke Gunther, Fietkau Rainer
机构信息
Medical Faculty, Department of Radiotherapy, University of Rostock, Germany.
出版信息
J Thorac Oncol. 2008 Jun;3(6):652-5. doi: 10.1097/JTO.0b013e3181757a76.
PMID:18520807
Abstract
This single-center study investigated the prevalence of brain metastases immediately before prophylactic cranial irradiation in 40 consecutive limited disease small cell lung cancer complete responders to chemoradiotherapy and revealed that 13/40 (32.5%; 95% confidence interval: 18-47%) patients suffer relapse with brain metastases and show a significantly worse prognosis than those without detected brain metastases.
摘要
这项单中心研究调查了40例连续的局限期小细胞肺癌患者在接受预防性颅脑照射前脑转移的发生率，这些患者均为放化疗的完全缓解者。结果显示，13/40（32.5%；95%置信区间：18-47%）的患者出现脑转移复发，且其预后明显比未检测到脑转移的患者更差。
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