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创伤后脑脊液瘘的一种有效且侵入性较小的治疗方法:闭式腰椎引流系统。

An effective and less invasive treatment of post-traumatic cerebrospinal fluid fistula: closed lumbar drainage system.

作者信息

Dalgic A, Okay H O, Gezici A R, Daglioglu E, Akdag R, Ergungor M F

机构信息

2nd Neurosurgery Clinic, Ankara Numune Research and Training Hospital, Ankara, Turkey.

出版信息

Minim Invasive Neurosurg. 2008 Jun;51(3):154-7. doi: 10.1055/s-2008-1042437.

Abstract

Cerebrospinal fluid (CSF) leakage may develop when a defect is formed in dural layers by traumatic or iatrogenic processes. Traumatic CSF leakage was encountered in 2% of head injuries. CSF leakage is an associated feature of 12-30% of skull base fractures. Numerous treatment modalities are proposed for the management of CSF leaks. A closed lumbar drainage system (CLDS) is recommended as an alternative method to surgery for preventing complications related to leakage. In the present study, we report the clinical details of 46 patients who suffered from rhinorrhea/otorrhea (R/O), three of whom were urgently operated due to other causes like subdural hematoma and tension pneumocephalus. Leakage spontaneously ceased in 26 (60.4%) patients whereas CLDS insertion was found to be necessary in 17 patients. A prophylactic antibiotic regimen was started in the CLDS group and these patients were followed with daily CSF cell counts. Fifteen patients (88.2%) were successfully treated by CLDS, however meningitis developed in 2 patients (11.7%). Severe complications like meningitis could be avoided by a simple daily microbiological analysis of CSF.

摘要

当硬脑膜层因外伤或医源性过程形成缺损时,可能会发生脑脊液(CSF)漏。2%的头部损伤会出现外伤性脑脊液漏。脑脊液漏是12% - 30%颅底骨折的相关特征。针对脑脊液漏的处理提出了多种治疗方式。推荐使用封闭式腰椎引流系统(CLDS)作为手术的替代方法,以预防与漏液相关的并发症。在本研究中,我们报告了46例患有鼻漏/耳漏(R/O)患者的临床细节,其中3例因硬膜下血肿和气颅等其他原因紧急接受了手术。26例(60.4%)患者的漏液自行停止,而17例患者需要插入CLDS。CLDS组开始使用预防性抗生素方案,并对这些患者每日进行脑脊液细胞计数监测。15例患者(88.2%)通过CLDS成功治疗,但2例患者(11.7%)发生了脑膜炎。通过简单的每日脑脊液微生物学分析可以避免像脑膜炎这样的严重并发症。

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