Scarone P, Klap P, Héran F, Robert G
Department of Neurosurgery, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.
Minim Invasive Neurosurg. 2008 Jun;51(3):178-82. doi: 10.1055/s-2008-1073136.
The transsphenoidal approach is still the optimal procedure for intrasellar infradiaphragmatic craniopharyngiomas. It is also used by many to treat intrasellar tumors which have a suprasellar extension, especially when there is a cystic component. However, this approach is not routinely performed for supradiaphragmatic ones, which are mostly approached by a transcranial route, even if the related morbidity is higher. Endoscopic techniques now allow a better visualization and could permit a widening of indications for the transsphenoidal route to such tumors, especially in older patients.
We used an extended endonasal endoscopic approach in a 80-year-old man who was diagnosed with a purely supradiaphragmatic craniopharyngioma. Preoperative rapid deterioration of visual function was the primary indication for surgery. Subtotal resection of the tumor was accomplished, as confirmed by intraoperative direct visualization and postoperative MRI. A rapid amelioration of visual function was noted postoperatively.
Primary endoscopic endonasal surgery for supradiaphragmatic retrochiasmatic craniopharyngiomas in elderly patients could represent a safer approach associated with a lower operative morbidity when compared to transcranial surgery and better postoperative results when compared to conservative treatments currently used. More cases are needed to quantify the risk of CSF leakage, which is currently the main disadvantage of this procedure.
经蝶窦入路仍是鞍内膈下颅咽管瘤的最佳手术方式。许多人也用其治疗向鞍上扩展的鞍内肿瘤,尤其是存在囊性成分时。然而,对于膈上颅咽管瘤,即使经颅手术相关发病率更高,也不常规采用经蝶窦入路,大多采用经颅途径。现在内镜技术能实现更好的视野,可能会扩大经蝶窦入路对此类肿瘤的适应证范围,尤其是在老年患者中。
我们对一名80岁男性采用扩大经鼻内镜入路,该患者被诊断为单纯膈上颅咽管瘤。术前视力功能迅速恶化是手术的主要指征。肿瘤次全切除得以完成,术中直接观察及术后磁共振成像(MRI)均证实了这一点。术后视力功能迅速改善。
与经颅手术相比,老年患者膈上视交叉后颅咽管瘤的一期内镜经鼻手术可能是一种更安全的方法,手术发病率更低;与目前使用的保守治疗相比,术后效果更好。需要更多病例来量化脑脊液漏的风险,这是目前该手术的主要缺点。