Gandhi Rajiv, Davey J Roderick, Mahomed Nizar N
Division of Orthopedic Surgery, University of Toronto, Ontario, Canada.
J Arthroplasty. 2009 Jan;24(1):38-42. doi: 10.1016/j.arth.2008.01.299. Epub 2008 Feb 14.
We conducted meta-analysis of clinical studies of HA coated femoral stems in hip arthroplasty. After an exhaustive literature search, we abstracted relevant data on the outcomes of stem survival from aseptic loosening and Harris Hip scores. The risk ratios and mean differences with 95% confidence intervals (CI) are reported. 9 studies met our inclusion criteria for the analysis. The cumulative risk ratio for femoral stem survival from aseptic loosening was 1.0 (95% CI: 0.995 to 1.005) P = .98. The pooled mean difference for the Harris Hip scores (HHS) was 0.072 (95% CI: -0.062 to 0.206), P = .293. The results of this study demonstrate that there are no clinical benefits in the use of HA/porous coating over porous coating alone in primary hip arthroplasty.
我们对髋关节置换术中羟基磷灰石（HA）涂层股骨柄的临床研究进行了荟萃分析。在全面检索文献后，我们提取了有关无菌性松动导致的柄生存率及Harris髋关节评分结果的相关数据。报告了风险比及95%置信区间（CI）的平均差。9项研究符合我们纳入分析的标准。无菌性松动导致的股骨柄生存率的累积风险比为1.0（95%CI：0.995至1.005），P = 0.98。Harris髋关节评分（HHS）的合并平均差为0.072（95%CI：-0.062至0.206），P = 0.293。本研究结果表明，在初次髋关节置换术中，使用HA/多孔涂层相较于单独使用多孔涂层并无临床益处。
