Farmer S E J, Quine S M, Eccles R
Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, Wales, UK.
J Laryngol Otol. 2009 Mar;123(3):309-14. doi: 10.1017/S0022215108002818. Epub 2008 Jun 9.
To determine the efficacy of inferior turbinate coblation for the treatment of nasal obstruction.
Twenty patients awaiting submucosal diathermy to the inferior turbinates were recruited into the study. All underwent inferior turbinate coblation. Pre-operative and post-operative nasal function was investigated using posterior rhinomanometry and subjective symptom scales.
There was no significant increase in nasal conductance two weeks after inferior turbinate coblation (p = 0.159). However, three months after inferior turbinate coblation, median nasal conductance had increased significantly, from 203 to 324 cm3/s (p = 0.004). The median increase in nasal conductance was 73 cm3/s or 43.5 per cent. Post-operative visual analogue patients' reported post-operative visual analogue scales scores for nasal obstruction decreased significantly, both two weeks (p = 0.006) and three months after inferior turbinate coblation (p = 0.001) when compared to Pre-operative values. There was no change in the reported severity of rhinorrhoea, nasal itching or sneezing. There was a significant relationship (rho = -0.57, p = 0.014) between pre-operative nasal conductance and change in nasal conductance after inferior turbinate coblation.
This study confirms the short-term efficacy of inferior turbinate coblation for the treatment of nasal obstruction. The benefit was greatest in patients with lower pre-operative nasal conductance. Objective measures of nasal obstruction may be important when selecting patients for inferior turbinate coblation.
确定下鼻甲低温等离子消融术治疗鼻塞的疗效。
招募20例等待下鼻甲黏膜下透热疗法的患者进入本研究。所有患者均接受下鼻甲低温等离子消融术。使用后鼻测压法和主观症状量表对术前和术后的鼻腔功能进行研究。
下鼻甲低温等离子消融术后两周，鼻腔导纳无显著增加（p = 0.159）。然而，下鼻甲低温等离子消融术后三个月，鼻腔导纳中位数显著增加，从203 cm³/s增至324 cm³/s（p = 0.004）。鼻腔导纳的中位数增加了73 cm³/s，即43.5%。与术前值相比，术后视觉模拟评分法中患者报告的鼻塞术后视觉模拟评分在术后两周（p = 0.006）和下鼻甲低温等离子消融术后三个月（p = 0.001）均显著降低。流涕、鼻痒或打喷嚏的报告严重程度无变化。术前鼻腔导纳与下鼻甲低温等离子消融术后鼻腔导纳变化之间存在显著相关性（rho = -0.57，p = 0.014）。
本研究证实了下鼻甲低温等离子消融术治疗鼻塞的短期疗效。对于术前鼻腔导纳较低的患者，益处最大。在选择下鼻甲低温等离子消融术的患者时，鼻塞的客观测量指标可能很重要。
