Lemeneva N V, Sorokin V S, Lubnin A Iu
Anesteziol Reanimatol. 2008 Mar-Apr(2):22-6.
The paper analyzes the clinical effectiveness of various blood-sparing techniques (hypervolemic hemodilution, isovolemic hemodilution, and instrumental infusion of washed autoerythrocytes) in neurosurgical interventions (n = 93) in 89 patients. Hypervolemic hemodilution that remains, however, to be the method of choice for young and low-weight children has proved to be the least clinically effective as a method for blood saving. The blood-sparing effectiveness of isovolmic hemodilution and instrumental reinfusion of washed autoerythrocytes is about the same, but the efficiency of reinfusion was higher with a blood loss volume of more than 100% of the proper volume of circulating complexes. A combination of hemodilution and instrumental reinfusion of autoerythrocytes provides a summation of blood-sparing effects for the mechanisms of blood saving vary with these techniques. The use of any blood-sparing technique accelerates and worsens hemostatic disorders.