Kuczkowski Jerzy
Katedra i Klinika Chorób Uszu, Nosa, Gardła i Krtani AM w Gdańsku.
Otolaryngol Pol. 2007;61(5):769-73. doi: 10.1016/S0030-6657(07)70523-1.
Thrombophlebitis of dura venous sinuses is a rare intracranial complication of otitis media, which may be sometimes accompanied by symptoms or sepsis. Anatomical conditions and early diagnosis of this vascular complication determine the treatment modality. Aim of this study was the assessment of diagnostics and treatment of venous sinuses thrombophlebitis in acute and chronic otitis media considering anatomy and the venous sinuses and status of coagulation system. Otogenic thrombophlebitis may occur in lateral, transverse, upper and lower petrosal sinuses, and rarely in cavernous. In some cases thrombophlebitis proces may expand into brain or emissary mastoid veins. Lateral sinus thrombophlebitis in chronic otitis media usually appears clinically as septic fever, earache, and increasing neurologic signs. In acute otitis media when thrombophlebitis develops the patient complains about headache, high fever and visual acquity. Diagnosis of venous sinus thrombophlebitis is based on clinical signs, radiological imaging (CT scan, MRI), bacteriological examinations and laboratory biochemical tests. Contrast enhanced CT scan shows "delta sign". Septic thrombophlebitis sinus sigmoidei is caused by mixed bacterial flora. Surgical treatment in cases with septic thrombus consists of radical modiffied ear operation and lateral sinus exposure. Thrombectomy and jugular vein ligation is performed when sepsis or thrombus is present. Mastoidectomy and tympanic cavity drainage is performed in cases with lateral sinus thrombosis in acute mastoiditis. Intravenous antibiotics therapy should be continued for 2 weeks. Anticoagulants should be given taking into consideration parameters of coagulation system and the type of thrombus. Treatment results of venous sinuses thrombophlebitis are good if they are not accompanied by other intracranial complications.
硬脑膜静脉窦血栓形成是中耳炎罕见的颅内并发症,有时可能伴有症状或败血症。这种血管并发症的解剖学情况和早期诊断决定了治疗方式。本研究的目的是评估急性和慢性中耳炎中静脉窦血栓形成的诊断和治疗,同时考虑静脉窦的解剖结构以及凝血系统的状况。耳源性血栓形成可能发生在外侧窦、横窦、上下岩窦,很少发生在海绵窦。在某些情况下,血栓形成过程可能扩展至脑部或乳突导血管。慢性中耳炎中的外侧窦血栓形成在临床上通常表现为败血症发热、耳痛和神经体征加重。在急性中耳炎发生血栓形成时,患者会主诉头痛、高热和视力下降。静脉窦血栓形成的诊断基于临床体征、放射影像学检查(CT扫描、MRI)、细菌学检查和实验室生化检测。增强CT扫描显示“δ征”。乙状窦败血性血栓形成由混合菌群引起。对于有败血性血栓的病例,手术治疗包括改良乳突根治术和外侧窦暴露。存在败血症或血栓时进行血栓切除术和颈静脉结扎术。急性乳突炎合并外侧窦血栓形成时进行乳突切除术和鼓室引流。静脉抗生素治疗应持续2周。应根据凝血系统参数和血栓类型给予抗凝剂。如果不伴有其他颅内并发症,静脉窦血栓形成的治疗效果良好。