Phommasack Bounlay, Saklokham Khamhoung, Chanthavisouk Chitsavang, Nakhonesid-Fish Viengsavanh, Strandgaard Hanne, Montresor Antonio, Shuey Dean A, Ehrenberg John
National School Health Taskforce, Department of Hygiene and Prevention, Ministry of Health, Simuang Road, Vientiane Capital, Lao PDR.
Trans R Soc Trop Med Hyg. 2008 Dec;102(12):1201-6. doi: 10.1016/j.trstmh.2008.04.036. Epub 2008 Jun 12.
Infections with soil-transmitted helminths (STHs) are among the commonest infections in Lao PDR. Recent investigation in this country showed that intestinal helminths currently infect the majority of school-aged children. The Lao Government has addressed the problem by organizing regular anthelminthic chemotherapy with mebendazole 500mg for school and pre-school children in conjunction with health education activities incorporated into the national school curriculum. The school deworming campaign in Lao PDR reached a national coverage rate of 95% at a cost of US$0.124/head for two rounds of deworming per year. The programme operates under the umbrella of the national school health programme. After 1 year (two rounds of deworming) the intervention reduced the prevalence of Ascaris lumbricoides from 60% to 20% and of Trichuris trichiura from 42% to 31%. Although infection was not eliminated by the deworming interventions, over 90% of those children who remain infected had a 'light' infection. The virtual absence of high and moderate intensity infection demonstrates the effectiveness of periodical deworming in reducing morbidity due to STHs. We expect that additional rounds of deworming will further reduce the STH prevalence in Lao PDR.
土壤传播的蠕虫感染是老挝人民民主共和国最常见的感染之一。该国最近的调查显示,目前大多数学龄儿童都感染了肠道蠕虫。老挝政府通过为学童和学龄前儿童定期组织使用500毫克甲苯达唑进行驱虫化疗,并结合纳入国家学校课程的健康教育活动来解决这一问题。老挝人民民主共和国的学校驱虫运动全国覆盖率达到95%,每年两轮驱虫的成本为每人0.124美元。该项目在国家学校健康项目的框架下运作。经过1年(两轮驱虫),干预措施使蛔虫感染率从60%降至20%,鞭虫感染率从42%降至31%。虽然驱虫干预措施并未消除感染,但仍有超过90%的感染儿童为“轻度”感染。几乎没有高强度和中度强度感染的情况,这表明定期驱虫在降低土壤传播的蠕虫感染发病率方面是有效的。我们预计,额外的驱虫轮次将进一步降低老挝人民民主共和国的土壤传播的蠕虫感染率。