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冠状动脉旁路移植术的现状

Current status of coronary artery bypass grafting.

作者信息

Kobayashi Junjiro

机构信息

Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2008 Jun;56(6):260-7. doi: 10.1007/s11748-008-0251-x. Epub 2008 Jun 18.

Abstract

The number of cases of coronary artery bypass grafting (CABG) reached more than 21 000 in Japan in 2002, and the operative mortality decreased to less than 1%, including emergency operations. The annual number of CABGs in Japan declined 17% after 2003 to 18 000 cases in 2005 owing to unrestricted percutaneous coronary intervention (PCI) with drug-eluting stents. However, CABG is the best treatment for multivessel coronary artery disease based on the comparative data of PCI versus CABG. There have been two trends in CABG during the last decade. One is the widespread use of off-pump (OP) CABG, and the other is multiple coronary artery revascularization. In 2004 and 2005, approximately 60% of all isolated CABG procedures in Japan were performed without cardiopulmonary bypass. In a study of long-term outcomes comparing PCI with drug-eluting stents versus CABG with only arterial grafts, the latter was carried out in 52% of total cases and in 66% of OPCAB cases. OPCAB with multiple arterial grafts has become the standard CABG in Japan.

摘要

2002年,日本冠状动脉搭桥术(CABG)的病例数超过21000例,手术死亡率降至1%以下,包括急诊手术。2003年后,由于药物洗脱支架的经皮冠状动脉介入治疗(PCI)不受限制,日本每年的CABG病例数下降了17%,2005年降至18000例。然而,基于PCI与CABG的比较数据,CABG是多支冠状动脉疾病的最佳治疗方法。在过去十年中,CABG出现了两种趋势。一种是不停跳(OP)CABG的广泛应用,另一种是多支冠状动脉血运重建。2004年和2005年,日本所有单纯CABG手术中约60%是在不进行体外循环的情况下进行的。在一项比较药物洗脱支架PCI与仅使用动脉移植物的CABG长期疗效的研究中,后者占总病例的52%,在不停跳CABG病例中占66%。多支动脉移植物的不停跳CABG已成为日本CABG的标准术式。

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