Ishibashi Nobuyuki, Aoki Mitsuru, Watanabe Manabu, Nakajima Hiromichi, Aotsuka Hiroyuki, Fujiwara Tadashi
Department of Cardiovascular Surgery, Chiba Children's Hospital, Chiba, Japan.
J Card Surg. 2008 Sep-Oct;23(5):488-92. doi: 10.1111/j.1540-8191.2008.00629.x. Epub 2008 Jun 28.
The purpose of this study was to identify the risk factor of interim failure and to consider the method for detecting high-risk patients after Blalock-Taussing shunt.
Between 1990 and 2004, 64 patients with functional single ventricle and low pulmonary flow underwent Blalock-Taussing shunt. We evaluated risk factors of interim failure by Logistic regression. Furthermore, assessments by catheterization and echocardiography were compared between Group Completion (Group C; 36 patients who had completed the Fontan operation or were Fontan candidates) and Group Failure (Group F; 20 patients who died before the Fontan operation or dropped out from Fontan candidate).
In Group C, the survival at 10 years was 93%. The risk factor of interim failure was a systemic ventricular end-diastolic volume (SVEDV) of more than 250% of normal after shunt. The ventricular volume by echocardiography in Group C had been maintained between 190% and 200% of normal. By contrast, the ventricle in Group F had been significantly dilated after postshunt short term.
The risk factor of interim failure was postshunt ventricular dilation, and the dilation was identified after postshunt short term. We recommend volume study within two to three months after shunt, and bidirectional cavopulmonary anastomosis should be immediately indicated to patients with ventricular dilation.
本研究旨在确定中期失败的风险因素,并探讨检测Blalock-Taussig分流术后高危患者的方法。
1990年至2004年间,64例功能性单心室且肺血流量低的患者接受了Blalock-Taussig分流术。我们通过逻辑回归评估中期失败的风险因素。此外,比较了完成组(C组;36例已完成Fontan手术或为Fontan手术候选者的患者)和失败组(F组;20例在Fontan手术前死亡或退出Fontan手术候选者的患者)之间通过心导管检查和超声心动图进行的评估。
在C组中,10年生存率为93%。中期失败的风险因素是分流术后体心室舒张末期容积(SVEDV)超过正常的250%。C组通过超声心动图测得的心室容积维持在正常的190%至200%之间。相比之下,F组的心室在分流术后短期内明显扩张。
中期失败的风险因素是分流术后心室扩张,且这种扩张在分流术后短期内即可识别。我们建议在分流术后两到三个月内进行容量研究,对于心室扩张的患者应立即进行双向腔肺吻合术。