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[急性肺脓肿发病机制中的免疫紊乱]

[Immunologic disorders in the pathogenesis of acute lung abscesses].

作者信息

Abisheeva A B, Kozachenko N V

出版信息

Klin Med (Mosk). 1991 May;69(5):58-60.

PMID:1857079
Abstract

Immune response was investigated in patients with acute pulmonary abscesses (APA) treated according to the discrete-dynamic scheme. The study of pathogenetic significance of immune response and chronic alcohol intoxication in APA demonstrated that failure of antiinfectious resistance of the body is one of the factors responsible for the onset, course and outcome of APA. This failure is characterized by unbalance of immune parameters, strain of immune system which is more pronounced in the presence of chronic alcoholic intoxication. It is evident that suppression of immune system shown in APA patients is an underlying cause of immunity deficiency in them.

摘要

对按照离散动力学方案治疗的急性肺脓肿(APA)患者的免疫反应进行了研究。对APA中免疫反应和慢性酒精中毒的发病机制意义的研究表明,机体抗感染抵抗力的下降是导致APA发生、发展和转归的因素之一。这种下降的特征是免疫参数失衡,免疫系统的应激在慢性酒精中毒存在时更为明显。显然,APA患者中表现出的免疫系统抑制是其免疫缺陷的根本原因。

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