Gupta T D, Jain V K, Tandon P N
Department of Electrical Engineering, Harcourt Butler Technological Institute, Kanpur, India.
Med Biol Eng Comput. 1991 Mar;29(2):113-20. doi: 10.1007/BF02447095.
Pulsed electromagnetic fields have been widely used for treatment of non-united fractures and congenital pseudarthrosis. Several electrical stimulation systems such as air-cored and iron-cored coils and solenoids have been used the world over and claimed to be effective. Electrical parameters such as pulse shape, magnitude and frequency differ widely, and the exact bone-healing mechanism is still not clearly understood. The study attempts to analytically investigate the effectiveness of various parameters and suggests an optimal stimulation waveform. Mathematical analysis of electric fields inside the bone together with Fourier analysis of induced voltage waveforms produced by commonly used electrical stimulation wave-forms has been performed. A hypothesis based on assigning different weightings to different frequencies for osteogenic response has been proposed. Using this hypothesis astonishingly similar effective values of electric fields have been found in different systems. It is shown that effective electric field rather than peak electric field is the main parameter responsible for osteogenesis. The results are in agreement with experimental findings made on human beings by different investigators.
脉冲电磁场已被广泛用于治疗骨折不愈合和先天性假关节。世界各地使用了几种电刺激系统，如空心线圈、铁芯线圈和螺线管，并声称其有效。诸如脉冲形状、幅度和频率等电参数差异很大，确切的骨愈合机制仍不清楚。该研究试图通过分析来研究各种参数的有效性，并提出一种最佳刺激波形。已对骨内电场进行数学分析，并对常用电刺激波形产生的感应电压波形进行傅里叶分析。提出了一种基于对不同频率的成骨反应赋予不同权重的假设。利用这一假设，在不同系统中发现了惊人相似的电场有效值。结果表明，有效电场而非峰值电场是促成骨的主要参数。这些结果与不同研究者对人类进行的实验结果一致。
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