Schaffner Nils, Wittwer Amrei, Kut Elvan, Folkers Gerd, Benninger David H, Candia Victor
Collegium Helveticum, University of Zurich and ETH Zurich, Schmelzbergstrasse 25, CH-8092 Zurich, Switzerland.
Neurosci Lett. 2008 Aug 8;440(3):309-13. doi: 10.1016/j.neulet.2008.05.084. Epub 2008 May 28.
Pain threshold and pain tolerance of heat noxious stimuli were assessed to determine whether they are equivalent when measured at three equidistant sites of both volar forearms. Heat pain threshold and tolerance were measured in 18 healthy volunteers using a standard stimulation device consisting of a thermode. Pain threshold and pain tolerance did not differ within and across forearm sites. Experimenters addressing heat pain threshold and tolerance in healthy volunteers may freely choose and change stimulation sites on both volar forearms, without the risk of confounding site effects on dependent variables. This data completes previous reports on side effects by analyzing the effect of site on the forearm for both heat pain threshold and tolerance. The absence of side and site effects may contribute to setting a more secure basis for assessments of laterality effects of painful stimulation.
评估热伤害性刺激的疼痛阈值和疼痛耐受性，以确定在双侧前臂三个等距部位进行测量时它们是否相等。使用由热刺激器组成的标准刺激装置，对18名健康志愿者进行热痛阈值和耐受性测量。前臂各部位之间以及不同前臂部位之间的疼痛阈值和疼痛耐受性没有差异。研究健康志愿者热痛阈值和耐受性的实验者可以自由选择并改变双侧前臂的刺激部位，而不会有混淆部位对因变量影响的风险。该数据通过分析前臂部位对热痛阈值和耐受性的影响，完善了之前关于副作用的报告。无侧别和部位效应可能有助于为评估疼痛刺激的侧别效应奠定更可靠的基础。
