Indes Jeffrey E, Lipsitz Evan C, Veith Frank J, Gargiulo Nicholas J, Privrat Alysia I, Eisdorfer Jacob, Scher Larry A
Division of Vascular Surgery, Department of Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
J Vasc Surg. 2008 Aug;48(2):286-90. doi: 10.1016/j.jvs.2008.03.057. Epub 2008 Jun 24.
This study examined the frequency and nature of incidental findings seen on computed tomography (CT) scans during preoperative and postoperative follow-up in patients undergoing endovascular aortic aneurysm repair (EVAR).
Between January 1, 2000, and March 1, 2006, 176 consecutive patients who underwent EVAR at our institution were retrospectively reviewed. Patients were included in the study if all preoperative and postoperative surveillance CT scans were performed at our institution. Eighty-two patients, 26 women (32%) and 56 men (68%), met this criterion. Their mean age was 76 years (range, 51-103 years). Official CT scan reports were reviewed. Findings were considered primary incidental if they were noted on preoperative CT scans and secondary incidental if they appeared on surveillance CT scans but not on the preoperative study. Primary and secondary incidental findings were considered either benign (eg, gallstones, diverticulosis) or clinically significant if they warranted further workup (eg, suspicious masses or changes suggestive of malignancy, internal or diaphragmatic hernias, and diverticulitis). The median follow-up was 29 months (range, 3-60 months). Each incidental finding was counted only once, on the first scan in which it appeared.
Of the 82 patients, 73 (89%) had at least one primary incidental finding, and 14 (19%) of these were clinically significant. Secondary incidental findings, many of which were clinically significant, continued to appear throughout the follow-up period. The most common clinically significant primary incidental finding was the presence of a lung mass (n = 4). The most common clinically significant secondary incidental findings were lung mass (n = 6), liver mass (n = 6), and pancreas mass (n = 3). There was a significant difference in the proportion of men to women in the group with clinically significant incidental findings vs the group without clinically significant incidental findings (P = .03959). Differences between the groups with respect to age or aneurysm size were not significant.
CT scans yielded surprisingly large numbers of both primary and secondary incidental findings, many of which were clinically significant. Primary incidental findings were more common than secondary incidental findings; however, clinically significant findings were found at a consistent rate throughout the study period.
本研究调查了接受血管腔内主动脉瘤修复术(EVAR)的患者在术前和术后随访的计算机断层扫描(CT)中偶然发现的频率和性质。
回顾性分析2000年1月1日至2006年3月1日期间在本机构连续接受EVAR治疗的176例患者。若所有术前和术后监测CT扫描均在本机构进行,则将患者纳入研究。82例患者符合该标准,其中26例女性(32%),56例男性(68%)。他们的平均年龄为76岁(范围51 - 103岁)。查阅了官方CT扫描报告。若在术前CT扫描中发现,则将其视为原发性偶然发现;若在监测CT扫描中出现但术前检查未发现,则视为继发性偶然发现。原发性和继发性偶然发现被视为良性(如胆结石、憩室病)或若需要进一步检查则具有临床意义(如可疑肿块或提示恶性肿瘤的变化、内疝或膈疝、憩室炎)。中位随访时间为29个月(范围3 - 60个月)。每个偶然发现在首次出现的扫描中仅计数一次。
82例患者中,73例(89%)至少有一项原发性偶然发现,其中14例(19%)具有临床意义。继发性偶然发现,其中许多具有临床意义,在整个随访期间持续出现。最常见的具有临床意义的原发性偶然发现是肺部肿块(n = 4)。最常见的具有临床意义的继发性偶然发现是肺部肿块(n = 6)、肝脏肿块(n = 6)和胰腺肿块(n = 3)。具有临床意义的偶然发现组与无临床意义的偶然发现组中男性与女性的比例存在显著差异(P = 0.03959)。两组在年龄或动脉瘤大小方面的差异不显著。
CT扫描产生了数量惊人的原发性和继发性偶然发现,其中许多具有临床意义。原发性偶然发现比继发性偶然发现更常见;然而,在整个研究期间,具有临床意义的发现率保持一致。