Nishiuchi Tatsuya, Hayashino Yasuaki, Fukuhara Shunichi, Iwami Taku, Hayashi Yasuyuki, Hiraide Atsushi, Ikeuchi Hisashi, Yukioka Hidekazu, Matsuoka Tetsuya
Osaka Prefectural Senshu Critical Care Medical Center, 2-24 Rinku-Orai Kita, Izumisano City, Osaka 598-0048, Japan.
Resuscitation. 2008 Sep;78(3):307-13. doi: 10.1016/j.resuscitation.2008.04.001. Epub 2008 Jun 24.
We reassessed 1-month survival of patients with witnessed out-of-hospital cardiac arrest (OHCA) of cardiac origin with ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT) in Osaka, Japan, and identified factors associated with 1-month survival using updated data from 1998 to 2004 collected based on the Utstein Style.
Using the Utstein Osaka Project database, we analyzed 1028 cases which met the following criteria: (1) patient age 18 years or older; (2) presumed cardiac origin based on the definition of the Utstein Style; (3) witnessed by citizens; (4) VF or pulseless VT at the time of arrival of the ambulance. The main outcome measure was survival at 1 month after collapse. Variables to develop a predictive model for 1-month survival were selected by stepwise logistic regression.
Survival at 1 month was 19.6%. Factors retained in the final logistic regression were age, sex, type of witness, and time interval from (a) ambulance call receipt to cardiopulmonary resuscitation (CPR) by the ambulance crew; (b) ambulance call to defibrillation; (c) CPR by the ambulance crew to hospital arrival. Area under the receiver-operating characteristic curve for the model developed with the six variables was 0.738 and Hosmer-Lemshow goodness-of-fit p-value was 0.94.
We successfully developed a model to estimate the probability of 1-month survival using variables easy to collect in the early phase of resuscitation, and this model would help physicians and family members predict the likelihood of 1-month survival of OHCA patients on admission.
我们重新评估了日本大阪心脏原因导致的院外心脏骤停(OHCA)伴心室颤动(VF)或无脉性室性心动过速(VT)患者的1个月生存率,并利用基于Utstein模式收集的1998年至2004年的最新数据确定了与1个月生存率相关的因素。
使用Utstein大阪项目数据库,我们分析了1028例符合以下标准的病例:(1)患者年龄18岁及以上;(2)根据Utstein模式的定义推断为心脏原因;(3)由市民目击;(4)救护车到达时为VF或无脉性VT。主要结局指标是晕倒后1个月的生存率。通过逐步逻辑回归选择用于建立1个月生存率预测模型的变量。
1个月生存率为19.6%。最终逻辑回归中保留的因素有年龄、性别、目击者类型以及从(a)接到救护电话到救护人员进行心肺复苏(CPR)的时间间隔;(b)救护电话到除颤的时间间隔;(c)救护人员进行CPR到医院到达的时间间隔。用这六个变量建立的模型的受试者操作特征曲线下面积为0.738,Hosmer-Lemshow拟合优度p值为0.94。
我们成功建立了一个模型,使用复苏早期易于收集的变量来估计1个月生存率的概率,该模型将有助于医生和家属预测OHCA患者入院时1个月生存的可能性。