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心脏起源的院外目击性心脏骤停伴心室颤动和无脉性室性心动过速的1个月生存率及相关因素:大阪Utstein项目

Survival rate and factors associated with 1-month survival of witnessed out-of-hospital cardiac arrest of cardiac origin with ventricular fibrillation and pulseless ventricular tachycardia: the Utstein Osaka project.

作者信息

Nishiuchi Tatsuya, Hayashino Yasuaki, Fukuhara Shunichi, Iwami Taku, Hayashi Yasuyuki, Hiraide Atsushi, Ikeuchi Hisashi, Yukioka Hidekazu, Matsuoka Tetsuya

机构信息

Osaka Prefectural Senshu Critical Care Medical Center, 2-24 Rinku-Orai Kita, Izumisano City, Osaka 598-0048, Japan.

出版信息

Resuscitation. 2008 Sep;78(3):307-13. doi: 10.1016/j.resuscitation.2008.04.001. Epub 2008 Jun 24.

DOI:10.1016/j.resuscitation.2008.04.001
PMID:18573589
Abstract

OBJECTIVE

We reassessed 1-month survival of patients with witnessed out-of-hospital cardiac arrest (OHCA) of cardiac origin with ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT) in Osaka, Japan, and identified factors associated with 1-month survival using updated data from 1998 to 2004 collected based on the Utstein Style.

METHODS

Using the Utstein Osaka Project database, we analyzed 1028 cases which met the following criteria: (1) patient age 18 years or older; (2) presumed cardiac origin based on the definition of the Utstein Style; (3) witnessed by citizens; (4) VF or pulseless VT at the time of arrival of the ambulance. The main outcome measure was survival at 1 month after collapse. Variables to develop a predictive model for 1-month survival were selected by stepwise logistic regression.

RESULTS

Survival at 1 month was 19.6%. Factors retained in the final logistic regression were age, sex, type of witness, and time interval from (a) ambulance call receipt to cardiopulmonary resuscitation (CPR) by the ambulance crew; (b) ambulance call to defibrillation; (c) CPR by the ambulance crew to hospital arrival. Area under the receiver-operating characteristic curve for the model developed with the six variables was 0.738 and Hosmer-Lemshow goodness-of-fit p-value was 0.94.

CONCLUSION

We successfully developed a model to estimate the probability of 1-month survival using variables easy to collect in the early phase of resuscitation, and this model would help physicians and family members predict the likelihood of 1-month survival of OHCA patients on admission.

摘要

目的

我们重新评估了日本大阪心脏原因导致的院外心脏骤停(OHCA)伴心室颤动(VF)或无脉性室性心动过速(VT)患者的1个月生存率,并利用基于Utstein模式收集的1998年至2004年的最新数据确定了与1个月生存率相关的因素。

方法

使用Utstein大阪项目数据库,我们分析了1028例符合以下标准的病例:(1)患者年龄18岁及以上;(2)根据Utstein模式的定义推断为心脏原因;(3)由市民目击;(4)救护车到达时为VF或无脉性VT。主要结局指标是晕倒后1个月的生存率。通过逐步逻辑回归选择用于建立1个月生存率预测模型的变量。

结果

1个月生存率为19.6%。最终逻辑回归中保留的因素有年龄、性别、目击者类型以及从(a)接到救护电话到救护人员进行心肺复苏(CPR)的时间间隔;(b)救护电话到除颤的时间间隔;(c)救护人员进行CPR到医院到达的时间间隔。用这六个变量建立的模型的受试者操作特征曲线下面积为0.738,Hosmer-Lemshow拟合优度p值为0.94。

结论

我们成功建立了一个模型,使用复苏早期易于收集的变量来估计1个月生存率的概率,该模型将有助于医生和家属预测OHCA患者入院时1个月生存的可能性。

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