Shah Archan M, Tidswell Mark, Prefontaine Michel, Skiest Daniel J, Pantanowitz Liron
Department of Medicine, Baystate Medical Center, Tufts University School of Medicine, 759 Chestnut Street - S2570, Springfield, MA 01199, USA.
Int J STD AIDS. 2008 Jul;19(7):496-8. doi: 10.1258/ijsa.2007.007133.
Choriocarcinoma is associated with high mortality in immunocompromised patients, in contrast to a good prognosis in immunocompetent individuals. Respiratory failure due to metatstatic choriocarcinoma is associated with high mortality in any patient. We report a case of a woman with AIDS that survived metastatic choriocarcinoma and respiratory failure. We also observed that in contrast to some in vitro studies, the markedly elevated levels of beta-subunit of human chorionic gonadotropin in this patient did not have any apparent inhibitory effect on viral replication.