吞噬信号传导:你可以触碰,但不能吞噬。

Phagocytic signaling: you can touch, but you can't eat.

作者信息

Kinchen Jason M, Ravichandran Kodi S

机构信息

Beirne Carter Center for Immunology Research, University of Virginia, Charlottesville, VA 22908, USA.

出版信息

Curr Biol. 2008 Jun 24;18(12):R521-4. doi: 10.1016/j.cub.2008.04.058.

Abstract

The ability of phagocytes to discriminate between viable/healthy and apoptotic/foreign/abnormal cells is of fundamental importance; a recent study provides new molecular insights into the function of CD47-SIRP alpha signaling in this discrimination.

摘要

吞噬细胞区分活的/健康的细胞与凋亡的/外来的/异常细胞的能力至关重要;最近的一项研究为CD47-SIRPα信号在这种区分中的功能提供了新的分子见解。

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