吞噬信号传导:你可以触碰,但不能吞噬。
Phagocytic signaling: you can touch, but you can't eat.
作者信息
Kinchen Jason M, Ravichandran Kodi S
机构信息
Beirne Carter Center for Immunology Research, University of Virginia, Charlottesville, VA 22908, USA.
出版信息
Curr Biol. 2008 Jun 24;18(12):R521-4. doi: 10.1016/j.cub.2008.04.058.
The ability of phagocytes to discriminate between viable/healthy and apoptotic/foreign/abnormal cells is of fundamental importance; a recent study provides new molecular insights into the function of CD47-SIRP alpha signaling in this discrimination.
吞噬细胞区分活的/健康的细胞与凋亡的/外来的/异常细胞的能力至关重要;最近的一项研究为CD47-SIRPα信号在这种区分中的功能提供了新的分子见解。