Abt Elliot
1Department of Dentistry, Illinois Masonic Medical Center, Chicago, USA.
Evid Based Dent. 2008;9(2):51-2. doi: 10.1038/sj.ebd.6400584.
Medline and manual searches were made of the bibliographies of all full-text articles and related reviews selected from the electronic search and the following journals: American Journal of Dentistry, Australian Dental Journal, British Journal of Oral and Maxillofacial Surgery, Clinical Implant Dentistry and Related Research, Clinical Oral Implants Research, Deutsche Zahnärztliche Zeitschrift, European Journal of Oral Sciences, International Dental Journal, International Journal of Oral and Maxillofacial Implants, International Journal of Periodontics and Restorative Dentistry, International Journal of Prosthodontics, Journal de Parodontologie, Journal of Clinical Periodontology, Journal of Dental Research, Journal of Oral Implantology, Journal of Oral Rehabilitation, Journal of Periodontology, Journal of Prosthetic Dentistry, Quintessence International, Swedish Dental Journal and Schweizerische Monatsschrift Zahnmedizin.
Prospective or retrospective cohort studies were included if they had a mean follow-up of 5 years or more; were reported in the dental literature in the English or German language; patients had been examined clinically at the follow-up visit; and details of the characteristics of the suprastructures were reported. Publications that combined findings for both implant-supported fixed partial dentures and single-tooth crowns were selected if they allowed for extraction of the data for the single-tooth crowns group. Publications based on patient records only or on questionnaires or interviews were excluded.
Failure and complication rates are calculated by dividing the number of events (failures or complications; the numerator) by the total exposure time [single crown (SC) time and/ or implant time; the denominator]. Event rates for SC and/ or implants were calculated by dividing the total number of events by the total SC or implant exposure time in years. The total number of events was considered to be Poisson distributed. To assess heterogeneity of the study-specific event rates, the Spearman goodness-of fit statistics and associated probability value were calculated. Multivariable Poisson regression was used to investigate formally whether event rates varied by crown material (metal-ceramic vs all-ceramic) or crown design (cemented vs screw-retained).
Twenty-six studies were included in the meta-analysis. Survival of implants supporting SC was 96.8% [95% confidence interval (CI), 95.9-97.6%] after 5 years. The survival rate of SC supported by implants was 94.5% (95% CI, 92.5-95.9%) after 5 years of function. The survival rate of metal-ceramic crowns, 95.4% (95% CI, 93.6-96.7%), was significantly higher (P 0.005) than the survival rate (91.2%; 95% CI, 86.8-94.2%), of all-ceramic crowns. Peri-implantitis and soft tissue complications occurred adjacent to 9.7% of the SC and 6.3% of the implants had bone loss exceeding 2 mm over the 5-year observation period. The cumulative incidence of implant fractures after 5 years was 0.14%. After 5 years, the cumulative incidence of screw or abutment loosening was 12.7%, and was 0.35% for screw or abutment fracture. For suprastructure-related complications, the cumulative incidence of ceramic or veneer fractures was 4.5%.
An observation period of 5 years allows the conclusion that high survival rates of implants and implant-supported SC can be expected, but biological and, particularly, technical complications are frequent.
对通过电子检索选出的所有全文文章及相关综述的参考文献进行了医学文献数据库(Medline)检索和手工检索,检索的期刊如下:《美国牙科杂志》《澳大利亚牙科杂志》《英国口腔颌面外科杂志》《临床种植牙科及相关研究》《临床口腔种植研究》《德国牙科杂志》《欧洲口腔科学杂志》《国际牙科杂志》《国际口腔颌面种植杂志》《国际牙周病与修复牙科杂志》《国际口腔修复学杂志》《牙周病学杂志》《临床牙周病学杂志》《牙科研究杂志》《口腔种植学杂志》《口腔修复学杂志》《牙周病学杂志》《口腔修复体学杂志》《精华国际》《瑞典牙科杂志》和《瑞士牙科医学月刊》。
纳入前瞻性或回顾性队列研究,条件为平均随访时间5年或更长;以英文或德文发表于牙科文献;患者在随访时接受了临床检查;并报告了上部结构的特征细节。如果能提取单冠组的数据,则选择那些综合了种植体支持的固定局部义齿和单冠研究结果的出版物。仅基于患者记录或问卷调查或访谈的出版物被排除。
失败率和并发症发生率通过将事件数(失败或并发症;分子)除以总暴露时间[单冠(SC)时间和/或种植体时间;分母]来计算。SC和/或种植体的事件发生率通过将事件总数除以SC或种植体的总暴露时间(以年为单位)来计算。事件总数被认为呈泊松分布。为评估各研究特定事件发生率的异质性,计算了斯皮尔曼拟合优度统计量及相关概率值。采用多变量泊松回归正式研究事件发生率是否因冠材料(金属陶瓷与全陶瓷)或冠设计(粘结式与螺丝固位式)而异。
荟萃分析纳入了26项研究。5年后,支持单冠的种植体存活率为96.8%[95%置信区间(CI),95.9 - 97.6%]。功能5年后,种植体支持的单冠存活率为94.5%(95%CI,92.5 - 95.9%)。金属陶瓷冠的存活率为95.4%(95%CI,93.6 - 96.7%),显著高于全陶瓷冠的存活率(91.2%;95%CI,86.8 - 94.2%)(P < 。0.005)。在5年观察期内,9.7%的单冠附近发生种植体周围炎和软组织并发症,6.3%的种植体骨吸收超过2mm。5年后种植体骨折的累积发生率为0.14%。5年后,螺丝或基台松动的累积发生率为12.7%,螺丝或基台骨折的累积发生率为0.35%。对于上部结构相关并发症,陶瓷或贴面骨折的累积发生率为4.5%。
5年的观察期可以得出结论,种植体和种植体支持的单冠有望获得较高的存活率,但生物并发症,尤其是技术并发症很常见。