Briko N I, Eshchina A S, Shikhman A R, Serna F R, Kondrakova O A, Smirnova M N, Dynga L O, Zhukov V V
Zh Mikrobiol Epidemiol Immunobiol. 1991 Jan(1):24-7.
459 blood donors aged 18-50 years were examined in 1987-1988 in Moscow. Among them, carrier state with respect to beta-hemolytic streptococci was detected in 107 donors (23.3%). The number of carriers gradually decreased with the increase of age of the examined donors. Group C streptococci occurred least of all (6.9%). Group A beta-hemolytic streptococci were isolated in 16.7% of the carriers. The isolation rate of streptococci from blood achieved its maximum in autumn and winter months and did not depend on preceding diseases, unhealthy working conditions, the rhesus factor and, with the exception of group A streptococci, the blood group. Among tonsillectomized donors carrier state with respect to beta-hemolytic streptococci occurred 2.2 times less frequently than among donors who had not undergone tonsillectomy. Carrier state with respect to beta-hemolytic streptococci was accompanied by higher levels of salivary sIgA antibodies to polysaccharide A, serum antibodies to polysaccharide A and circulating polysaccharide A. All beta-hemolytic streptococci were sensitive to erythromycin. All groups of streptococci showed the highest percentage of cultures resistant to gentamicin and tetracycline. In 100% of cases group A streptococci were sensitive to benzylpenicillin, methicillin, ampicillin, erythromycin and lincomycin.
1987年至1988年期间，在莫斯科对459名年龄在18至50岁的献血者进行了检查。其中，107名献血者（23.3%）检测出携带β溶血性链球菌。随着受检献血者年龄的增加，携带者的数量逐渐减少。C组链球菌出现的比例最低（6.9%）。A组β溶血性链球菌在16.7%的携带者中被分离出来。血液中链球菌的分离率在秋冬季节达到最高，且与既往疾病、不健康的工作条件、恒河猴因子以及除A组链球菌外的血型无关。在接受扁桃体切除的献血者中，携带β溶血性链球菌的情况比未接受扁桃体切除的献血者少2.2倍。携带β溶血性链球菌与唾液中针对多糖A的分泌型免疫球蛋白A抗体、血清中针对多糖A的抗体以及循环多糖A水平较高有关。所有β溶血性链球菌对红霉素敏感。所有组别的链球菌对庆大霉素和四环素耐药的培养物比例最高。100%的A组链球菌对苄青霉素、甲氧西林、氨苄青霉素、红霉素和林可霉素敏感。
