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[皮脂腺癌。两例病例研究]

[Sebaceous carcinoma. Study of two cases].

作者信息

Iglesias I, Troyano J, Díaz-Valle D, Genol I

机构信息

Departamento de Oculoplastia, Hospital Clínico San Carlos, Madrid, España.

出版信息

Arch Soc Esp Oftalmol. 2008 Jul;83(7):445-8. doi: 10.4321/s0365-66912008000700011.

Abstract

CLINICAL CASES

A 94-year-old woman, who had had a chalazion for a period of 8 months, presented because of thickening of the eyelid with necrosis, madarosis and adenopathy. A 67-year-old woman, previously operated on for a sebaceous carcinoma, presented because of reddening of the conjunctiva and eyelid. Clinical evaluation revealed inflammation of the eyelid and an irregular and erythematous superior bulbar conjunctiva with disruption of the limbal architecture.

DISCUSSION

A sebaceous carcinoma is a tumour which is difficult to diagnose and treat, because it can be patchy and has a tendency to pagetoid dissemination. Diagnosis requires a biopsy of the lesion and mapping of biopsies from the conjunctiva of the eyelid and eyebrow. The subsequent treatment depends on the extent of the tumour, and may involve simple cleavage, topical mitomycin C, radiotherapy or exenteration of the eyebrow.

摘要

临床病例

一名94岁女性,睑板腺囊肿已有8个月,因眼睑增厚伴坏死、睫毛脱落及淋巴结肿大前来就诊。一名67岁女性,曾接受过皮脂腺癌手术,因结膜和眼睑发红前来就诊。临床评估显示眼睑炎症,上睑球结膜不规则且发红,角膜缘结构破坏。

讨论

皮脂腺癌是一种难以诊断和治疗的肿瘤,因为它可能呈片状,并有派杰样扩散的倾向。诊断需要对病变进行活检,并对眼睑和眉毛结膜的活检部位进行定位。后续治疗取决于肿瘤的范围,可能包括单纯切除、局部应用丝裂霉素C、放疗或眉毛切除。

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