Kaneko Masahiro, Tomioka Hiromi, Kaneda Toshihiko, Kubot Mio, Tani Shigenori, Fujii Hiroshi, Katsuyama Eiji, Okazaki Miki
Department of Respiratory Medicine, Kobe City Medical Center West Hospital.
Nihon Kokyuki Gakkai Zasshi. 2008 Jun;46(6):505-9.
A 46-year-old woman was referred to our hospital because of abnormal findings of 18F-fluorodeoxyglucose-PET (FDG-PET) scan at a medical check-up. Her chest radiography and CT showed nodular shadows distributed along the broncho-vascular bundle. The 1st FDG-PET showed a high FDG uptake in the pulmonary nodules, and the hilar, mediastinal and supraclavicular lymph nodes. Although sarcoidosis was suspected, diagnosis was not obtained by bronchoscopy. Thoracoscopic lung biopsy was performed in order to exclude malignancy, resulting in a definite diagnosis of sarcoidosis. No treatment was given and subsequently spontaneous regression was obtained. The follow-up FDG-PET showed no abnormal uptake at all. FDG-PET has been widely used in the assessment of malignancy, however recent reports have indicated that sarcoid lesions could have increased FDG activity. FDG-PET may be useful for diagnosis and monitoring in sarcoidosis.
一名46岁女性因体检时18F-氟脱氧葡萄糖-PET（FDG-PET）扫描结果异常而转诊至我院。她的胸部X线和CT显示沿支气管血管束分布的结节状阴影。首次FDG-PET显示肺结节、肺门、纵隔和锁骨上淋巴结有高FDG摄取。尽管怀疑为结节病，但支气管镜检查未明确诊断。为排除恶性肿瘤进行了胸腔镜肺活检，最终确诊为结节病。未给予治疗，随后病情自发缓解。随访FDG-PET显示完全没有异常摄取。FDG-PET已广泛用于恶性肿瘤评估，然而最近的报告表明结节病病变可能有FDG活性增加。FDG-PET可能有助于结节病的诊断和监测。
