血液的起源：不同来源造血干细胞的诱导

The origins of blood: induction of hematopoietic stem cells from different sources.

作者信息

Saito Yoriko, Ishikawa Fumihiko

机构信息

Research Unit for Human Disease Models, RIKEN Research Center for Allergy and Immunology, 1-7-22 Suehiro-cho Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

出版信息

Cell Stem Cell. 2008 Jul 3;3(1):8-10. doi: 10.1016/j.stem.2008.06.008.

DOI:10.1016/j.stem.2008.06.008

PMID:18593553

Abstract

Ex vivo hematopoiesis from embryonic sources offers exciting promises in basic research and medicine. In this issue of Cell Stem Cell, Ledran et al. (2008) describe human embryonic stem cell (hESC)-derived hematopoiesis, while Taoudi et al. (2008) define the origin of definitive hematopoietic stem cells (HSCs) from the mouse aorta-gonad-mesonephros (AGM) region.

摘要

源自胚胎的体外造血在基础研究和医学领域展现出了令人兴奋的前景。在本期《细胞·干细胞》杂志中，莱德兰等人（2008年）描述了人胚胎干细胞（hESC）衍生的造血过程，而陶迪等人（2008年）则明确了小鼠主动脉-性腺-中肾（AGM）区域中确定性造血干细胞（HSCs）的起源。