Poon Kin-Shing, Wu King-Chuen, Chen Chia-Chen, Fung Si-Tun, Lau Albert Wai-Cheung, Huang Chiu-Chen, Wu Rick Sai-Chuen
Department of Anesthesia, Pain Service and Critical Care Medicine, China Medical University Hospital, Taichung, Taiwan, R.O.C.
Acta Anaesthesiol Taiwan. 2008 Jun;46(2):57-60. doi: 10.1016/S1875-4597(08)60026-0.
Hypertension and fluctuations in blood pressure (BP) during lumbar spinal surgery in the prone position under anesthesia are not unusual. The purpose of this study was to investigate the causes of the decrease in BP during lumbar spinal surgery in the prone position using a noninvasive monitor of cardiac output.
Twenty ASA Class I or II patients, scheduled for elective lumbar spinal surgery in the prone position, had their hemodynamic status monitored by a BioZ.com system Impedance Cardiograph during anesthesia. Hemodynamic data (heart rate [HR], mean BP, cardiac index [CI], stroke volume [SV] and systemic vascular resistance [SVR]) were registered at baseline, post-induction of general anesthesia, 10 minutes after the patient was turned from the supine to the prone position and 1 hour after the start of surgery. Friedman's test and the paired t test were used to compare the collected data on hemodynamic parameters.
The mean BP, SV, CI and HR were found to have significant differences (p < 0.05) at the designated time points as analyzed by Friedman's test, while the SVR and central venous pressure showed no significant changes. CI and SV were found to be markedly decreased from 2.4 +/- 0.3 to 2.0 +/- 0.3 L/minute/m2 and from 45.8 +/- 9.7 to 36.7 +/- 9.2 mL, respectively, after patients assumed the prone position. Mean BP also decreased significantly. After 1 hour of surgery, the mean BP decreased further with a fall in HR but the SV remained unchanged.
Decreases in SV and CI are the main causes of a decrease in BP in the prone position during lumbar spinal surgery.
在麻醉下俯卧位进行腰椎手术期间,高血压和血压波动并不罕见。本研究的目的是使用无创心输出量监测仪调查俯卧位腰椎手术期间血压下降的原因。
20例计划在俯卧位进行择期腰椎手术的美国麻醉医师协会(ASA)I或II级患者,在麻醉期间通过BioZ.com系统阻抗心动图监测其血流动力学状态。在基线、全身麻醉诱导后、患者从仰卧位转为俯卧位10分钟以及手术开始1小时后记录血流动力学数据(心率[HR]、平均血压、心脏指数[CI]、每搏输出量[SV]和全身血管阻力[SVR])。采用Friedman检验和配对t检验比较收集的血流动力学参数数据。
经Friedman检验分析,在指定时间点平均血压、SV、CI和HR有显著差异(p<0.05),而SVR和中心静脉压无显著变化。发现患者转为俯卧位后,CI和SV分别从2.4±0.3显著降至2.0±0.3L/分钟/平方米和从45.8±9.7显著降至36.7±9.2mL。平均血压也显著下降。手术1小时后,平均血压随着HR下降进一步降低,但SV保持不变。
SV和CI降低是俯卧位腰椎手术期间血压下降的主要原因。