Devi P, George J
Department of Pharmacology, St John's Medical College, Bangalore, India.
Kathmandu Univ Med J (KUMJ). 2008 Jan-Mar;6(1):23-7.
Diabetic Nephropathy is a leading cause of end stage renal disease. Doctors often have questions during patient care when they are advised to seek the best available evidence. Rational drug use demands access to unbiased drug information. This study was conducted to delineate and analyse the patient-specific drug information needs of physicians treating diabetic nephropathy in Nephrology ward of a south Indian tertiary care hospital.
A prospective, observational study was conducted in the Department of Nephrology in St John's Medical College, Bangalore from 1st October 2003 to 31st March 2004. The relevant data regarding patient- specific queries of physicians on drug information were collected by joining physicians on clinical rounds and analysed.
Out of 102 patients included in the study, physicians had queries on 66% of patients. The total number of queries was 80. The average number of queries per nephrologist was 9 and those per physician were 10. Queries on adverse drug reactions and drug interactions exceeded (31%) others. Queries on anti-hypertensive drugs were the maximum (33%) followed by antimicrobials (12.5%). About 93% of queries were answered. Tertiary sources (51%) were the most commonly used drug information sources. The mean time to find the answer to a query was about 30 minutes.
Physicians treating DN are in need of drug information services, especially on adverse drug reactions and drug interactions during in-patient care. The majority of queries of physicians treating diabetic nephropathy can be answered by referring authentic drug information sources.
糖尿病肾病是终末期肾病的主要病因。在患者护理过程中,当医生被建议寻求最佳现有证据时,他们常常会有疑问。合理用药需要获取无偏倚的药物信息。本研究旨在描述和分析印度南部一家三级护理医院肾病科治疗糖尿病肾病的医生针对患者的特定药物信息需求。
2003年10月1日至2004年3月31日,在班加罗尔圣约翰医学院肾病科进行了一项前瞻性观察研究。通过与医生一起进行临床查房,收集有关医生针对患者药物信息的特定疑问的相关数据并进行分析。
在纳入研究的102名患者中,医生对66%的患者有疑问。疑问总数为80个。每位肾病科医生的平均疑问数为9个,每位医生的平均疑问数为10个。关于药物不良反应和药物相互作用的疑问超过其他疑问(31%)。关于抗高血压药物的疑问最多(33%),其次是抗菌药物(12.5%)。约93%的疑问得到了解答。三级来源(51%)是最常用的药物信息来源。找到疑问答案的平均时间约为30分钟。
治疗糖尿病肾病的医生需要药物信息服务,尤其是住院护理期间有关药物不良反应和药物相互作用的信息。参考可靠的药物信息来源可以回答大多数治疗糖尿病肾病医生的疑问。