腹裂畸形患儿16至24个月大时的生长发育及神经发育情况。

Growth and neurodevelopment at 16 to 24 months of age for infants born with gastroschisis.

作者信息

South A P, Marshall D D, Bose C L, Laughon M M

机构信息

Department of Pediatrics, Division of Neonatal-Perinatal Medicine, School of Medicine, University of North Carolina at Chapel Hill, NC 27599-7596, USA.

出版信息

J Perinatol. 2008 Oct;28(10):702-6. doi: 10.1038/jp.2008.71. Epub 2008 Jul 10.

DOI:10.1038/jp.2008.71

PMID:18615088

Abstract

OBJECTIVE

To examine growth, neurodevelopment and morbidity in infants with gastroschisis.

STUDY DESIGN

We enrolled all infants with gastroschisis treated at the North Carolina Children's Hospital from March 2003 through June 2005. Neonatal data were collected. Medical history, growth and neurodevelopment were assessed at 16 to 24 months.

RESULT

Of 24 infants, 17 completed follow-up. Weight and length were below the 10th percentile for five and six infants, respectively. Three infants scored less than 85 on the Bayley Scales of Infant Development, second edition. Small for gestational age (SGA) infants were smaller and had lower neurodevelopmental scores. Fourteen experienced continued bowel dysfunction; nine were rehospitalized.

CONCLUSION

One-third of infants with gastroschisis experience growth delay. Infants who are SGA are at higher risk, suggesting that postnatal growth may be influenced by fetal phenomena, and may not be modifiable. Neurodevelopment is not delayed. Continued bowel dysfunction is common.

摘要