Gauthey D, Morisod J, Coutaz M
Centre de gériatrie du Bas-Valais, Clinique St-Amé, Route des Cases, 1890 Saint-Maurice.
Rev Med Suisse. 2008 May 7;4(156):1167-71.
We present the case of a end stage renal failure patient treated with haemodialysis who developed painful nodules of the subcutis which progressed to ulcerative and necrotic lesions, gradually spreading. The diagnosis of calcific uremic arteriolopathy was made, based on histologic findings showing adipose tissue with necrotic areas and calcifications of the arterioles's media. We describe the clinical presentation of this syndrome which is associated with a high mortality and resume the actual conceptions about the pathogenesis, the diagnosis, prevention and treatment.
我们报告了一例接受血液透析治疗的终末期肾衰竭患者的病例,该患者出现了皮下疼痛性结节,这些结节进展为溃疡性和坏死性病变,并逐渐扩散。基于组织学检查结果,即脂肪组织出现坏死区域且小动脉中层钙化,做出了钙化性尿毒症小动脉病的诊断。我们描述了这种与高死亡率相关的综合征的临床表现,并概述了目前关于其发病机制、诊断、预防和治疗的观念。