一种双核钌（II）配合物与艾滋病病毒RNA的TAR区域的结合。
Binding of a dinuclear ruthenium(ii) complex to the TAR region of the HIV-AIDS viral RNA.
作者信息
Buck Damian P, Spillane Caitriona B, Collins J Grant, Keene F Richard
机构信息
School of Physical, Environmental and Mathematical Sciences, University College, University of New South Wales, Australian Defence Force Academy, Canberra, ACT 2600, Australia.
出版信息
Mol Biosyst. 2008 Aug;4(8):851-4. doi: 10.1039/b803216e. Epub 2008 Jun 3.
DOI:10.1039/b803216e
PMID:18633486
Abstract
Molecular modelling has identified a new RNA conformational feature created by the insertion of bulge residues into duplex regions that may act as a recognition site for small molecule binding, in particular for inert dinuclear ruthenium complexes.
摘要
分子建模已确定了一种新的RNA构象特征，该特征是由在双链区域插入凸起残基所产生的，这可能充当小分子结合的识别位点，特别是对于惰性双核钌配合物而言。
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