心肌分子成像的细胞内和细胞外靶点。

Intracellular and extracellular targets of molecular imaging in the myocardium.

作者信息

Chun Hyung J, Narula Jagat, Hofstra Leonard, Wu Joseph C

机构信息

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305-5344, USA.

出版信息

Nat Clin Pract Cardiovasc Med. 2008 Aug;5 Suppl 2:S33-41. doi: 10.1038/ncpcardio1161.

DOI:10.1038/ncpcardio1161

PMID:18641605

Abstract

Utilization of molecular imaging has significantly advanced the field of cardiovascular medicine. In addition to the targets currently in use, novel targets are being developed, including those involved in the processes of myocardial metabolism, myocardial injury, cardiac neurotransmission, and interstitial dysregulation. Further development of these imaging targets may lead to improved characterization of disease processes and guide provision of individualized therapies.

摘要

分子成像技术的应用显著推动了心血管医学领域的发展。除了目前正在使用的靶点外，新型靶点也在不断研发中，包括那些参与心肌代谢、心肌损伤、心脏神经传递和间质调节异常过程的靶点。这些成像靶点的进一步发展可能会改善对疾病过程的特征描述，并指导个性化治疗的提供。