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用于成人髋关节囊外骨折的伽马钉及其他髁头髓内钉与髓外植入物的比较

Gamma and other cephalocondylic intramedullary nails versus extramedullary implants for extracapsular hip fractures in adults.

作者信息

Parker Martyn J, Handoll Helen H G

机构信息

Orthopaedic Department, Peterborough and Stamford Hospitals NHS Foundation Trust, Peterborough District Hospital, Thorpe Road, Peterborough, Cambridgeshire, UK, PE3 6DA.

出版信息

Cochrane Database Syst Rev. 2008 Jul 16(3):CD000093. doi: 10.1002/14651858.CD000093.pub4.

Abstract

BACKGROUND

Two types of implants used for the surgical fixation of extracapsular hip fractures are cephalocondylic intramedullary nails, which are inserted into the femoral canal proximally to distally across the fracture, and extramedullary implants (e.g. the sliding hip screw).

OBJECTIVES

To compare cephalocondylic intramedullary nails with extramedullary implants for extracapsular hip fractures in adults.

SEARCH STRATEGY

We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (June 2007), the Cochrane Central Register of Controlled Trials (The Cochrane Library 2007, Issue 2), MEDLINE (1966 to June week 3 2007), EMBASE (1988 to 2007 Week 27), the UK National Research Register, orthopaedic journals, conference proceedings and reference lists of articles.

SELECTION CRITERIA

All randomised and quasi-randomised controlled trials comparing cephalocondylic nails with extramedullary implants for extracapsular hip fractures.

DATA COLLECTION AND ANALYSIS

Both authors independently assessed trial quality and extracted data. Wherever appropriate, results were pooled.

MAIN RESULTS

Predominantly older people with mainly trochanteric fractures were treated in the 36 included trials.Twenty-two trials (3871 participants) compared the Gamma nail with the sliding hip screw (SHS). The Gamma nail was associated with an increased risk of operative and later fracture of the femur and an increased reoperation rate. There were no major differences between implants in the wound infection, mortality or medical complications.Five trials (623 participants) compared the intramedullary hip screw (IMHS) with the SHS. Fracture fixation complications were more common in the IMHS group; all cases of operative and later fracture of the femur occurred in this group. Results for post-operative complications, mortality and functional outcomes were similar in the two groups. Three trials (394 participants) showed no difference in fracture fixation complications, reoperation, wound infection and length of hospital stay for proximal femoral nail (PFN) compared with the SHS. Single trials compared the Targon PF nail versus SHS (60 participants); experimental mini-invasive static intramedullary nail versus SHS (60 participants); Kuntscher-Y nail versus SHS (230 participants); Gamma nail versus Medoff sliding plate (217 participants); and PFN versus Medoff sliding plate (203 participants). These trials provided insufficient evidence to establish differences between these implants. Two trials (65 participants with reverse and transverse fractures at the level of the lesser trochanter) found intramedullary nails (Gamma nail or PFN) were associated with better intra-operative results and fewer fracture fixation complications than extramedullary implants (a 90-degree blade plate or dynamic condylar screw) for these fractures.

AUTHORS' CONCLUSIONS: Given the lower complication rate of the SHS in comparison with intramedullary nails, SHS appears superior for trochanteric fractures. Further studies are required to determine if different types of intramedullary nail produce similar results, or if intramedullary nails have advantages for selected fracture types (for example, subtrochanteric fractures).

摘要

背景

用于手术固定囊外髋部骨折的两种植入物为髁头髓内钉,其从股骨近端向远端插入股骨髓腔并穿过骨折部位,以及髓外植入物(如滑动髋螺钉)。

目的

比较成人囊外髋部骨折使用髁头髓内钉与髓外植入物的效果。

检索策略

我们检索了Cochrane骨、关节与肌肉创伤组专业注册库(2007年6月)、Cochrane对照试验中央注册库(《Cochrane图书馆》2007年第2期)、MEDLINE(1966年至2007年6月第3周)、EMBASE(1988年至2007年第27周)、英国国家研究注册库、骨科期刊、会议论文集以及文章的参考文献列表。

选择标准

所有比较髁头髓内钉与髓外植入物用于囊外髋部骨折的随机和半随机对照试验。

数据收集与分析

两位作者独立评估试验质量并提取数据。在适当情况下,对结果进行合并。

主要结果

纳入的36项试验中主要治疗的是老年人,主要为转子间骨折。22项试验(3871名参与者)比较了Gamma钉与滑动髋螺钉(SHS)。Gamma钉与股骨手术及后期骨折风险增加以及再次手术率升高相关。植入物在伤口感染、死亡率或医疗并发症方面无重大差异。5项试验(623名参与者)比较了髓内髋螺钉(IMHS)与SHS。骨折固定并发症在IMHS组更为常见;所有股骨手术及后期骨折病例均发生在该组。两组术后并发症、死亡率和功能结果相似。3项试验(394名参与者)表明,与SHS相比,股骨近端髓内钉(PFN)在骨折固定并发症、再次手术、伤口感染和住院时间方面无差异。单项试验比较了Targon PF钉与SHS(60名参与者);实验性微创静态髓内钉与SHS(60名参与者);Kuntscher - Y钉与SHS(230名参与者);Gamma钉与Medoff滑动钢板(217名参与者);以及PFN与Medoff滑动钢板(203名参与者)。这些试验提供的证据不足以确定这些植入物之间的差异。两项试验(65名小转子水平有反向和横向骨折的参与者)发现,对于这些骨折,髓内钉(Gamma钉或PFN)与髓外植入物(90度角钢板或动力髁螺钉)相比,术中效果更好且骨折固定并发症更少。

作者结论

鉴于SHS与髓内钉相比并发症发生率较低,SHS似乎在转子间骨折治疗方面更具优势。需要进一步研究以确定不同类型的髓内钉是否产生相似结果,或者髓内钉对于特定骨折类型(如转子下骨折)是否具有优势。

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