Minni A, Barbaro M, Vitolo D, Filipo R
Neurology and Otolaryngology Department, University of Rome La Sapienza, Rome, Italy.
Acta Otorhinolaryngol Ital. 2008 Jun;28(3):141-3.
Hibernoma is an unusual tumour of brown adipose tissue. Brown adipose tissue is common in mammalian hibernating animals and acts as a thermogenic organ. A first case of hibernoma was reported in 1906 by Merkel. This tumour usually arises in the back, shoulder region, mediastinum, retroperitoneum and in the neck. The neck location of hibernomas is rare and only 18 cases of cervical hibernoma have been reported in the English literature. A 48-year-old male with hoarseness and soft voice, present for 8 months, showed a lesion involving the anterior part of the right vocal fold, with no impaired mobility. This is the first case to be reported of laryngeal hibernoma located in a vocal fold, originating from the white fat tissue of the paraglottic space. Moreover, this report could be evidence of the development of hibernoma from white adipose tissue.
冬眠瘤是一种罕见的棕色脂肪组织肿瘤。棕色脂肪组织在哺乳动物冬眠动物中很常见，是一种产热器官。1906年默克尔首次报告了一例冬眠瘤病例。这种肿瘤通常发生在背部、肩部区域、纵隔、腹膜后和颈部。冬眠瘤发生在颈部的情况很少见，英文文献中仅报道了18例颈部冬眠瘤。一名48岁男性，声音嘶哑、嗓音柔和，症状持续8个月，检查发现右侧声带前部有病变，活动未受限。这是首例报告的位于声带的喉冬眠瘤，起源于声门旁间隙的白色脂肪组织。此外，本报告可能是冬眠瘤由白色脂肪组织发展而来的证据。
