用铂基DNA交联剂对DNA包裹的单壁碳纳米管进行非共价功能化。

Noncovalent functionalization of DNA-wrapped single-walled carbon nanotubes with platinum-based DNA cross-linkers.

作者信息

Ostojic Gordana N, Ireland John R, Hersam Mark C

机构信息

Department of Materials Science and Engineering, Northwestern University, Evanston, Illinois 60208-3108, USA.

出版信息

Langmuir. 2008 Sep 2;24(17):9784-9. doi: 10.1021/la801311j. Epub 2008 Jul 23.

DOI:10.1021/la801311j

PMID:18646876

Abstract

A method for noncovalent functionalization of DNA-wrapped single-walled carbon nanotubes (SWNTs) using platinum-based DNA cross-linkers is investigated. In particular, cisplatin and potassium tetrachloroplatinate are shown to bind to DNA that encapsulates SWNTs in aqueous solution. The bound platinum salt can then be reduced to decorate the DNA-encapsulated SWNTs with platinum nanoparticles. The resulting SWNT/DNA/Pt hybrids are investigated by optical absorption spectroscopy, circular dichroism spectroscopy, Raman spectroscopy, X-ray diffraction, transmission electron microscopy, and atomic force microscopy. The unique combination of catalytic activity of nanoscale platinum, biological functionality of DNA, and optoelectronic properties of SWNTs suggests a myriad of applications including fuel cells, catalysts, biosensors, and electrochemical devices.

摘要

研究了一种使用铂基DNA交联剂对DNA包裹的单壁碳纳米管（SWNTs）进行非共价功能化的方法。具体而言，顺铂和四氯铂酸钾被证明能与在水溶液中包裹SWNTs的DNA结合。然后，结合的铂盐可以被还原，用铂纳米颗粒修饰DNA包裹的SWNTs。通过光吸收光谱、圆二色光谱、拉曼光谱、X射线衍射、透射电子显微镜和原子力显微镜对所得的SWNT/DNA/Pt杂化物进行了研究。纳米级铂的催化活性、DNA的生物功能以及SWNTs的光电特性的独特组合表明其在燃料电池、催化剂、生物传感器和电化学装置等众多应用中具有潜力。