Prompers L, Huijberts M, Schaper N, Apelqvist J, Bakker K, Edmonds M, Holstein P, Jude E, Jirkovska A, Mauricio D, Piaggesi A, Reike H, Spraul M, Van Acker K, Van Baal S, Van Merode F, Uccioli L, Urbancic V, Ragnarson Tennvall G
Department of Internal Medicine, University Hospital Maastricht, P. Debyelaan 25, Maastricht, the Netherlands.
Diabetologia. 2008 Oct;51(10):1826-34. doi: 10.1007/s00125-008-1089-6. Epub 2008 Jul 22.
AIMS/HYPOTHESIS: The aim of the present study was to investigate resource utilisation and associated costs in patients with diabetic foot ulcers and to analyse differences in resource utilisation between individuals with or without peripheral arterial disease (PAD) and/or infection.
Data on resource utilisation were collected prospectively in a European multicentre study. Data on 1,088 patients were available for the analysis of resource use, and data on 821 patients were included in the costing analysis. Costs were calculated for each patient by multiplying the country-specific direct and indirect unit costs by the number of resources used from inclusion into the study up to a defined endpoint. Country-specific costs were converted into purchasing power standards.
Resource use and costs varied between outcome groups and between disease severity groups. The highest costs per patient were for hospitalisation, antibiotics, amputations and other surgery. All types of resource utilisation and costs increased with the severity of disease. The total cost per patient was more than four times higher for patients with infection and PAD at inclusion than for patients in the least severe group, who had neither.
CONCLUSIONS/INTERPRETATION: Important differences in resource use and costs were found between different patient groups. The costs are highest for individuals with both peripheral arterial disease and infection, and these are mainly related to substantial costs for hospitalisation. In view of the magnitude of the costs associated with in-hospital stay, reducing the number and duration of hospital admissions seems an attractive option to decrease costs in diabetic foot disease.
目的/假设:本研究的目的是调查糖尿病足溃疡患者的资源利用情况及相关成本,并分析有无外周动脉疾病(PAD)和/或感染的个体在资源利用方面的差异。
在一项欧洲多中心研究中前瞻性收集资源利用数据。有1088例患者的数据可用于资源使用分析,821例患者的数据纳入成本分析。通过将特定国家的直接和间接单位成本乘以从纳入研究到定义终点所使用的资源数量,计算每位患者的成本。特定国家的成本转换为购买力标准。
资源使用和成本在结局组和疾病严重程度组之间有所不同。每位患者最高的成本用于住院、抗生素、截肢和其他手术。所有类型的资源利用和成本都随着疾病严重程度的增加而增加。纳入研究时伴有感染和PAD的患者的人均总成本比最不严重组(既无感染也无PAD)的患者高出四倍多。
结论/解读:不同患者组在资源使用和成本方面存在重要差异。外周动脉疾病和感染患者的成本最高,且这些成本主要与住院的高额费用有关。鉴于与住院相关的成本规模,减少住院次数和住院时间似乎是降低糖尿病足疾病成本的一个有吸引力的选择。