Mierzejewski Andrzej, Eliks Iwona, Kałuzny Bartłomiej, Zygulska Maja, Harasimowicz Bartosz, Kałuzny Jakub J
Department of Ophthalmology, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Klin Oczna. 2008;110(1-3):11-7.
To evaluate the influence of recently performed cataract phacoemulsification in glaucomatous eyes on postoperative intraocular pressure (IOP).
100 eyes of 86 glaucoma patients who underwent cataract phacoemulsification with simultaneous intraocular lens implantation, were retrospectively analyzed. The patients were divided into two groups: I--61 patients (71 eyes) with open angle glaucoma, and II--25 patients (29 eyes) with angle closure glaucoma. Both groups were subdivided into two subgroups, depending on presence of symptoms of pseudoexfoliation (PEX) syndrome (A = with, and B = without symptoms of PEX syndrome). All patients were examined in the department where the surgeries were performed; before surgery, on the first day after the procedure, and again during the last follow-up examinations, 6 to 30 months after the procedure.
Before surgery, the intraocular pressure (IOP) was at mean value of 19.02 +/- 4.55 mmHg in group I, and 20.01 +/- 6.43 mmHg in group II. On the first day after surgery, the IOP was 17.42 +/- 7.17 and 20.36 +/- 8.98 mmHg, respectively. lOP exceeding 20 mmHg was found in 7 eyes in group I, and in 6 eyes in group II. During the last follow-up examinations the lOP was 14.59 +/- 3.73 and 14.01 +/- 4.50 mmHg, respectively, and was lower than measured before surgery, by an average of 4.43 mmHg in group I (P < 1 x 10(-5)), and 6.00 mmHg in group II (P < 1 x 10(-4)). In both groups, the reduction of lOP in patients with PEX was even more remarkable. The number of glaucoma medication necessary to control the pressure was reduced on average by 0.28 in group I, and 0.31 in group II.
Phacoemulsification done on glaucomatous eyes results in lowering of lOP, and hence the dosage of glaucoma drugs over the long term can be simplified or even discontinued.
评估近期在青光眼患者眼中进行的白内障超声乳化手术对术后眼压（IOP）的影响。
回顾性分析86例接受白内障超声乳化联合人工晶状体植入术的青光眼患者的100只眼睛。患者分为两组：I组——61例（71只眼）开角型青光眼患者，II组——25例（29只眼）闭角型青光眼患者。根据是否存在假性剥脱（PEX）综合征症状，两组又各自分为两个亚组（A = 有PEX综合征症状，B = 无PEX综合征症状）。所有患者均在手术科室接受检查；手术前、术后第一天以及术后6至30个月的最后一次随访检查时进行检查。
手术前，I组眼压平均为19.02±4.55 mmHg，II组为20.01±6.43 mmHg。术后第一天，I组眼压为17.42±7.17 mmHg，II组为20.36±8.98 mmHg。I组有7只眼眼压超过20 mmHg，II组有6只眼眼压超过20 mmHg。在最后一次随访检查时，I组眼压为14.59±3.73 mmHg，II组为14.01±4.50 mmHg，均低于手术前测量值，I组平均降低4.43 mmHg（P < 1×10⁻⁵），II组平均降低6.00 mmHg（P < 1×10⁻⁴）。在两组中，有PEX综合征的患者眼压降低更为显著。I组控制眼压所需的青光眼药物数量平均减少0.28，II组平均减少0.31。
青光眼患者进行超声乳化手术可降低眼压，因此长期来看青光眼药物的用量可以简化甚至停用。
