De Carlis L, Lauterio A, Giacomoni A, Slim A O, Pirotta V, Mangoni J, Mihaylov P
Hepato-biliary Surgery and Liver Transplantation Unit, Azienda Ospedaliera Niguarda Cà Granda, Milan, Italy.
Transplant Proc. 2008 Jul-Aug;40(6):1944-6. doi: 10.1016/j.transproceed.2008.05.051.
In right lobe living donor liver transplantation (ALDLT), reconstruction of middle hepatic vein (MHV) tributaries is often necessary to avoid severe graft congestion. From March 2001, we performed 36 right lobe ALDLT (segments 5, 6, 7, and 8) without MHV and one pediatric transplant (segments 2 and 3). In the presence of MHV tributaries larger than 5 mm, we intraoperatively evaluated the need for reconstruction. At a mean follow-up of 848 days (range=8-2412), 33/37 transplanted patients are alive with overall patient and graft survivals of 89.2% and 83.8%, respectively. Large MHV tributaries (>5 mm) were present in 10 cases, and inferior right hepatic veins (IRHV) draining segment 6 in 11 cases. In 10 cases, we performed an end-to-side anastomosis between the IRHV and the side of the recipient vena cava. In three cases, the MHV tributaries were end-to-end anastomosed to the stump of the recipient MHV. In all other cases, the vein tributaries were not reconstructed. A computed tomography scan performed from 1 to 3 months after surgery did not show any congested area in the liver parenchyma. In our experience, reconstruction of the MHV tributaries was not always necessary when graft-to-recipient weight ratio is >0.8. Pre- and intraoperative evaluation of the segmental branches of the hepatic vein is crucial to decide about reconstructing these collaterals. Anastomosis of V5 or V8 to the stump of the recipient MHV reduces the number of vascular anastomosis and maintains a physiological angle between these collaterals and the caval vein.
在右半肝活体供肝肝移植(ALDLT)中,为避免严重的移植物充血,肝中静脉(MHV)分支的重建通常是必要的。自2001年3月起,我们进行了36例无MHV的右半肝ALDLT(第5、6、7和8段)以及1例小儿移植(第2和3段)。当存在直径大于5mm的MHV分支时,我们在术中评估重建的必要性。平均随访848天(范围=8 - 2412天),37例移植患者中有33例存活,患者和移植物的总体生存率分别为89.2%和83.8%。10例存在粗大的MHV分支(>5mm),11例有引流第6段的右下肝静脉(IRHV)。10例中,我们将IRHV与受体腔静脉侧壁进行了端侧吻合。3例中,将MHV分支与受体MHV残端进行了端端吻合。在所有其他病例中,静脉分支未进行重建。术后1至3个月进行的计算机断层扫描未显示肝实质有任何充血区域。根据我们的经验,当移植物与受体重量比>0.8时,MHV分支的重建并非总是必要的。肝静脉节段分支的术前和术中评估对于决定是否重建这些侧支血管至关重要。将V5或V8与受体MHV残端吻合可减少血管吻合的数量,并保持这些侧支血管与腔静脉之间的生理角度。