Khder S A, Trifan Anca, Danciu M, Stanciu C
Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Medicină, Institutul de Gastroenterologie şi Hepatologie Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2008 Jan-Mar;112(1):59-65.
To evaluate the prevalence of colorectal polyps in a population from North- Eastern Romania, which underwent colonoscopic examination and to identify their clinical, endoscopic and histopathologic characteristics.
A retrospective prevalence study of subjects aged 18-95 years, with no personal or familial history of familial adenomatous polyposis and inflammatory bowel disease, who underwent a colonoscopy. The number, size, gross endoscopic appearance, histopathological examination, and the anatomic location of colorectal polyps were analyzed, as well as the associated diseases.
Enrolled were 1001 patients (647 men, 354 women), aged 18-95 years (mean: 62.8 +/- 11.4 years) who were diagnosed with colorectal polyps. Overall, there were 1.534 colorectal polyps, and the majority of them (83.0%) were present in patients over the age of 50 years, from urban area (73.9%) and most of the patients were men (63.8%), and had solitary polyps (61.1%). Three-quarters of polyps were distal (rectum, sigmoid, and descendent colon) in location, and most of them (75.8%) had a size less than 10 mm. Over half of all polyps (54.7%) were pedunculated. Based on the histological structural configuration, 76.5% of all polyps were adenomas, and of these 62.6% were tubular adenomas; malignant polyps have been diagnosed in 82 (5.4%) patients. Associated hemorrhoids, diverticulosis, colorectal cancer, and angiodysplasia were identified in 9.6%, 10% and 1.3%, respectively.
The prevalence of colorectal polyps in our geographical area is in the range with that observed in other regions of our country. Most of polyps were identified in patients older than 50 years, predominantly men, located in distal colon, had a tubular adenoma histological structure, and frequently associated with hemorrhoids and diverticular disease.
评估罗马尼亚东北部接受结肠镜检查人群中结直肠息肉的患病率，并确定其临床、内镜及组织病理学特征。
对年龄在18 - 95岁、无家族性腺瘤性息肉病及炎症性肠病个人或家族史且接受结肠镜检查的受试者进行一项回顾性患病率研究。分析了结直肠息肉的数量、大小、内镜大体表现、组织病理学检查、解剖位置以及相关疾病。
纳入1001例年龄在18 - 95岁（平均：62.8±11.4岁）被诊断为结直肠息肉的患者。总体上，共有1534个结直肠息肉，其中大多数（83.0%）存在于50岁以上患者中，来自城市地区（73.9%），大多数患者为男性（63.8%），且为单发息肉（61.1%）。四分之三的息肉位于远端（直肠、乙状结肠和降结肠），其中大多数（75.8%）大小小于10毫米。超过一半的息肉（54.7%）有蒂。根据组织结构，所有息肉中76.5%为腺瘤，其中62.6%为管状腺瘤；82例（5.4%）患者被诊断为恶性息肉。分别有9.6%、10%和1.3%的患者伴有痔疮、憩室病、结直肠癌和血管发育异常。
我们地区结直肠息肉的患病率与我国其他地区观察到的范围一致。大多数息肉在50岁以上患者中被发现，主要为男性，位于结肠远端，具有管状腺瘤组织结构，且常与痔疮和憩室病相关。
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