Burger A, Birkhäuser M
Schweiz Med Wochenschr. 1976 Sep 4;106(36):1210-2.
The etiology and diagnosis of Grave's disease are briefly reviewed with particular reference to newer discoveries in the wide range of immunoglobulins which might act as humoral stimulators of the thyroid. Diagnosis of hyperthyroidism has been greatly facilitated by radioimmunologic determination of serum T4 and T3 and indirect estimation of T4 (T4 index). In this way 85-90% of cases can be diagnosed with a single blood sample. TRH tests and T3 suppression tests are only rarely required.
本文简要回顾了格雷夫斯病的病因及诊断，特别提及了在种类繁多的免疫球蛋白方面的最新发现，这些免疫球蛋白可能作为甲状腺的体液刺激物。血清T4和T3的放射免疫测定以及T4的间接估计（T4指数）极大地促进了甲状腺功能亢进症的诊断。通过这种方法，85%至90%的病例仅用一份血样即可确诊。促甲状腺激素释放激素试验和T3抑制试验很少需要。
