Ye Zhou, Tao Ling, Fan Zhao-pu, Wu Jin-ping, Wang Ying
Emergency Center of Kalamay Hospital, Kalamay 834000, Xinjiang Autonomous Region, China.
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2008 Aug;20(8):476-8.
To simplify the acute physiology and chronic health evaluation II (APACHE II) score to make it more suitable for emergency patients.
Medical records of all the dead patients in the intensive care unit (ICU) from January 2003 to October 2005 were retrospectively analyzed. Those dead patients whose clinical data were completed for study were chosen as the experimental group (153 cases). Patients who survived in the same ICU at the same period were chosen as cohort for comparison. The worst scores within 24 hours of admission were selected for comparison between survivors and non-survivors to establish the modified APACHE II by linear regression. Then the new score was tested in the emergency patients who needed medical care from January to October 2006, and the accuracy of the prognostic value was evaluated.
Tested by the Lemeshow-Hosmer C-statistic and calibration curve analysis, the modified APACHE II score showed a good clustering data and the high calibration of the potential death of the nonsurvivors (chi2=8.853, P=0.335). If 16 being the forecasting point, the modified APACHE II score showed that sensitivity of the model in forecasting the dead patients from the emergency patients was 86.8% with an exclusivity of 81.6% and accuracy of 81.8%. The scores of the modified APACHE II paralleled with severity of the patients conditions, suggesting that the patients with lower scores were inclined to be discharged early or with a shorter period of hospitalization, while those with higher scores, the possibility of prolonged hospitalization or even death might ensue. In another words, the higher scores the higher risk of death.
The modified APACHE II score could be conveniently used in emergency patients with high reliability.
简化急性生理与慢性健康状况评分系统II(APACHE II),使其更适用于急诊患者。
回顾性分析2003年1月至2005年10月重症监护病房(ICU)所有死亡患者的病历。选取临床资料完整可用于研究的死亡患者作为实验组(153例)。选取同期在同一ICU存活的患者作为对照队列。选择入院24小时内的最差评分在存活者和非存活者之间进行比较,通过线性回归建立改良的APACHE II评分。然后将新评分应用于2006年1月至10月需要医疗护理的急诊患者,并评估其预后价值的准确性。
经Lemeshow-Hosmer C统计量和校准曲线分析检验,改良的APACHE II评分显示出良好的数据聚类性以及对非存活者潜在死亡的高校准性(χ2 = 8.853,P = 0.335)。以16分为预测点时,改良的APACHE II评分显示该模型预测急诊死亡患者的敏感性为86.8%,特异性为81.6%,准确性为81.8%。改良的APACHE II评分与患者病情严重程度平行,表明评分较低的患者倾向于早期出院或住院时间较短,而评分较高的患者则可能出现住院时间延长甚至死亡的情况。换句话说,评分越高死亡风险越高。
改良的APACHE II评分可方便地用于急诊患者,可靠性高。