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[前往热带地区儿童的免疫接种:被忽视的疫苗]

[Immunization for children travelling to the tropics: neglected vaccines].

作者信息

Imbert P, Guérin N, Sorge F

机构信息

Service des maladies infectieuses et tropicales, Hôpital d'Instruction des Armées Bégin, Saint-Mandé, France.

出版信息

Med Trop (Mars). 2008 Jun;68(3):231-5.

Abstract

Each year hundreds of thousands of children leave France to travel to developing countries where they are exposed to infectious agents that can be prevented by vaccination. During the child's pre-travel check-up, practitioners should check that all mandatory immunizations are up-to-date and provide advice on relevant vaccines in function of the epidemiological situation at the chosen destination. However various factors hinder full compliance with this approach and some vaccines are underused. Underused vaccines are referred to as neglected vaccines. In the French vaccination schedule three vaccinations can be considered as neglected. The first is the hepatitis B vaccine that has a low coverage level in France due to strong reluctance to its use despite the fact that the virus is widespread in tropical areas. The second is pneumococcal vaccine that should be administered to all infants less than 2 years of age, especially for travel to areas where pneumonia and meningitis are frequent. The third is BCG vaccine that is now at greater risk of being neglected in child travellers because its use has been downgraded from a general requirement to a recommendation only for children at risk. A serious limitation on the use of travel vaccinations is cost that can lead families to neglect some infectious risk such as hepatitis A that is a major risk for child travellers as well as for their relatives during or after the trip and typhoid fever that is essentially an imported disease. Rabies vaccine is also underused due to its cost and to poor understanding of the risk by many practitioners and families. The purpose of this article is to underline the need to improve information and access to vaccines that are all too often neglected in child travellers.

摘要

每年都有数十万儿童离开法国前往发展中国家,在那里他们会接触到可通过接种疫苗预防的感染源。在儿童旅行前的体检中,医生应检查所有强制性免疫接种是否在有效期内,并根据选定目的地的流行病学情况提供有关相关疫苗的建议。然而,各种因素阻碍了这种方法的全面实施,一些疫苗未得到充分利用。未充分利用的疫苗被称为被忽视的疫苗。在法国的疫苗接种计划中,有三种疫苗可被视为被忽视的疫苗。第一种是乙型肝炎疫苗,尽管该病毒在热带地区广泛传播,但由于人们对其使用强烈抵触,在法国的接种覆盖率较低。第二种是肺炎球菌疫苗,应接种给所有2岁以下的婴儿,特别是前往肺炎和脑膜炎高发地区旅行的婴儿。第三种是卡介苗,现在儿童旅行者中被忽视的风险更大,因为其使用已从一般要求降级为仅建议给有风险的儿童。旅行疫苗使用的一个严重限制是成本,这可能导致家庭忽视一些感染风险,如甲型肝炎,这对儿童旅行者及其亲属在旅行期间或旅行后都是主要风险,还有伤寒热,这基本上是一种输入性疾病。狂犬病疫苗也因成本以及许多医生和家庭对风险的认识不足而未得到充分利用。本文的目的是强调需要改善信息获取并增加儿童旅行者经常被忽视的疫苗的可及性。

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